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Supelco

Fumonisin B1

reference material, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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Synonym(s):
Fumonisin B1 from Fusarium moniliforme, Macrofusine
Empirical Formula (Hill Notation):
C34H59NO15
CAS Number:
116355-83-0
Molecular Weight:
721.83
MDL number:
MFCD27977580
UNSPSC Code:
85151701
PubChem Substance ID:
329754397
NACRES:
NA.24

grade

analytical standard
reference material

Quality Level

200

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

InChI

1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21-,22+,23+,24+,25+,26-,27-,32+/m0/s1

InChI key

UVBUBMSSQKOIBE-DSLOAKGESA-N

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General description

Fumonisins are a family of mycotoxins that are characterized by their structurally related homologs. They are generally produced by fungi of Fusarium species.

Application

Fumonisin B1 may be used as an analytical reference standard for the determination of the analyte in:
  • Swine liver by high performance liquid chromatography-fluorescence detection (HPLC-FLD).
  • Cereals by HPLC.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Fungal metabolite believed to cause leukoencephalomalacia in horses.

Analysis Note

purity : ≥92.5% (HPLC)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H351,H361d,H373

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2 - Repr. 2 - STOT RE 2

Target Organs

Kidney,Liver

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

高风险级别生物产品--毒素类产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Influence of experimental parameters on the fluorescence response and recovery of the high-performance liquid chromatography analysis of fumonisin B1.
Samapundo S, et al.
Journal of Chromatography A, 1109(2), 312-316 (2006)
Candida P Shirima et al.
Environmental health perspectives, 123(2), 173-178 (2014-10-18)
Aflatoxin and fumonisin are toxic food contaminants. Knowledge about effects of their exposure and coexposure on child growth is inadequate. We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. A total of 166 children were
Shijia Wu et al.
Analytical chemistry, 84(14), 6263-6270 (2012-07-24)
We presented a new aptasensor for mycotoxins, which was based on multiplexed fluorescence resonance energy transfer (FRET) between multicolor upconversion fluorescent nanoparticles (UCNPs) as donors and graphene oxide (GO) as the entire and effective acceptor. BaY(0.78)F(5):Yb(0.2), Er(0.02) and BaY(0.78)F(5):Yb(0.7), Tm(0.02)
B Gaspardo et al.
Food chemistry, 135(3), 1608-1612 (2012-09-08)
Fourier transform near infrared (FT-NIR) spectroscopy is an analytical procedure generally used to detect organic compounds in food. In this work the ability to predict fumonisin B(1)+B(2) contents in corn meal using an FT-NIR spectrophotometer, equipped with an integration sphere
Anil Chuturgoon et al.
Toxicology, 315, 65-69 (2013-11-28)
Fumonisin B1 (FB1), a common mycotoxin contaminant of maize, is known to inhibit sphingolipid biosynthesis and has been implicated in cancer promoting activity in animals and humans. FB1 disrupts DNA methylation and chromatin modifications in human hepatoma (HepG2) cells. We
View All Related Papers

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