All Photos(2)
Synonym(s):
α-(4-Fluorophenyl)-4-(2-pyridinyl)-1-piperazinebutanol, 1-(4-Fluorophenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)butan-1-ol
Empirical Formula (Hill Notation):
C19H24FN3O
CAS Number:
Molecular Weight:
329.41
Beilstein:
568396
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
OC(CCCN1CCN(CC1)c2ccccn2)c3ccc(F)cc3
InChI
1S/C19H24FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10,18,24H,3-4,11-15H2
InChI key
LVXYAFNPMXCRJI-UHFFFAOYSA-N
General description
Azaperol is one of the major metabolites of azaperone which is used as a tranquilizer.
Application
Azaperol may be used as an analytical reference standard for the determination of the analyte in:
- Pig tissues by liquid chromatography–tandem mass spectrometry (LC-MS/MS).
- Egg, fish and meat samples by high-resolution liquid chromatography coupled to time-of-flight mass spectrometry (HRLC-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
J C Jaen et al.
Journal of medicinal chemistry, 36(24), 3929-3936 (1993-11-26)
The enantiomers of reduced haloperidol (3a), azaperol (3b), and the related compound BMY-14802 (3c) were prepared in high optical purity. The affinity of these compounds for dopamine D2 and D3 receptors, and sigma S1 and S2 sites was determined in
M L Olmos-Carmona et al.
Journal of chromatography. B, Biomedical sciences and applications, 734(1), 113-120 (1999-11-26)
A method for analysis of veterinary tranquillizers in urine using gas chromatography-mass spectrometry (GC-MS) is described. Detection limits are 5 microg/l for ketamine, azaperone and the phenothiazines (chlor-, aceto- and propionylpromazine), 10 microg/l for haloperidol, 20 microg/l for xylazine and
L A Adam
Journal of AOAC International, 82(4), 815-824 (1999-08-13)
The method described confirms the use of the tranquilizer azaperone by detecting the parent compound and the metabolically reduced form, azaperol. Both are confirmed in swine liver at a target concentration of 10 ppb by gas chromatography/mass spectrometry (GC/MS) with
W Arneth
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 201(3), 261-265 (1995-09-01)
A method is described for the analytical determination of the neuroleptics azaperone (plus its metabolite azaperol), acetylpromazine, propionylpromazine, chlorpromazine and the beta-blocking agent carazolol in pork kidneys. These compounds may be used illegally to calm pigs during their transport to
Multi-residue screening of veterinary drugs in egg, fish and meat using high-resolution liquid chromatography accurate mass time-of-flight mass spectrometry.
Peters RJB, et al.
Journal of Chromatography A, 1216(46), 8206-8216 (2009)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service