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Baquiloprim

VETRANAL®, analytical standard

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Synonym(s):
5-{[8-(Dimethylamino)-7-methyl-5-quinolinyl]methyl}-2,4-pyrimidinediamine
Empirical Formula (Hill Notation):
C17H20N6
CAS Number:
102280-35-3
Molecular Weight:
308.38
MDL number:
MFCD00864859
UNSPSC Code:
41116107
PubChem Substance ID:
329754045
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CN(C)c1c(C)cc(Cc2cnc(N)nc2N)c3cccnc13

InChI

1S/C17H20N6/c1-10-7-11(8-12-9-21-17(19)22-16(12)18)13-5-4-6-20-14(13)15(10)23(2)3/h4-7,9H,8H2,1-3H3,(H4,18,19,21,22)

InChI key

AIOWJIMWVFWROP-UHFFFAOYSA-N

Related Categories

General description

Baquiloprim is a diaminopyrimidine derivative used as an antibiotic in veterinary medicine.

Application

Baquiloprim may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by solid-phase extraction (SPE) and hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS).
  • Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction and liquid chromatography coupled to time-of-flight mass spectrometry (LC-TOF-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Microbial screening methods for detection of antibiotic residues in slaughter animals.
Pikkemaat M.
Analytical and Bioanalytical Chemistry, 395(4), 893-905 (2009)
G White et al.
Research in veterinary science, 54(3), 372-378 (1993-05-01)
During examination of the half-lives in cattle of a series of 5-substituted diaminobenzyl-pyrimidines, it was found that replacement of the phenyl ring of trimethoprim (TMP) by bicyclic structures, particularly a quinolyl group, led to increases in half-life. The presence of
D G White et al.
The Veterinary record, 143(10), 273-276 (1998-10-27)
Thirty-eight, one- to two-week-old calves with experimentally induced Escherichia coli diarrhoea were randomly assigned to three treatment groups. Two groups of 15 calves were treated intramuscularly once daily for three days with either danofloxacin mesylate at 1.25 mg/kg bodyweight, or
Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Dasenaki ME, et al.
Journal of Chromatography A, 1452(4), 67-80 (2016)
C Svensson
Veterinary parasitology, 74(2-4), 143-152 (1998-04-30)
Twelve calves aged 6-10 months, and 12 calves aged 10-16 months were turned out onto a permanent pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous year. Two days after turnout, six of the older
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