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Merck
CN

32553

Tinidazole

VETRANAL®, analytical standard

Synonym(s):

1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C8H13N3O4S
CAS Number:
19387-91-8
Molecular Weight:
247.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329754026
EC Number:
243-014-4
Beilstein/REAXYS Number:
618182
MDL number:
MFCD00057217

Key Documents

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Product Name

Tinidazole, VETRANAL®, analytical standard

Quality Level

100

InChI

1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

InChI key

HJLSLZFTEKNLFI-UHFFFAOYSA-N

SMILES string

CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tinidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Tablet formulations and human serum samples by reversed phase-high performance liquid chromatography (RP-HPLC).

General description

Tinidazole belongs to the family of nitroimidazole compounds.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2 - Muta. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7696
BCCG3896
BCCC5372
BCBZ8493
BCBV9140

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Separation and assay o f antiprotozoal imidazole derivatives (metronidazole, tinidazole and secnidazole) by RP-HPLC.
Alhalabi Z, et al.
International Journal of Pharmaceutical Sciences Review and Research, 13(1), 13-18 (2012)
Multi-residue method for the detection of veterinary drugs in distillers grains by liquid chromatography-Orbitrap high resolution mass spectrometry.
Kaklamanos G, et al.
Journal of Chromatography A, 1322, 38-48 (2013)
Simultaneous estimation of ciprofloxacin hydrochloride, ofloxacin, tinidazole and ornidazole by reverse phase-high performance liquid chromatography.
Singh R, et al.
Eurasian Journal of Analytical Chemistry, 4(2), 161-167 (2009)
Elizabeth A Bosserman et al.
Sexually transmitted diseases, 38(10), 983-987 (2011-09-22)
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of
Alessandro Federico et al.
Gastroenterology, 143(1), 55-61 (2012-04-10)
Helicobacter pylori have become resistant to antimicrobial agents, reducing eradication rates. A 10-day sequential regimen that contains levofloxacin was efficient, safe, and cost saving in eradicating H pylori infection in an area with high prevalence of clarithromycin resistance. We performed
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