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32442

Supelco

Amitraz Metabolite BTS 27271

PESTANAL®, analytical standard

Synonym(s):

N-(2,4-Dimethylphenyl)-N′-methylformamidine, N-Methyl-N′-2,4-xylylformamidine

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About This Item

Empirical Formula (Hill Notation):
C10H14N2
CAS Number:
33089-74-6
Molecular Weight:
162.23
Beilstein:
1210087
MDL number:
MFCD00225755
UNSPSC Code:
41116107

grade

analytical standard

product line

PESTANAL®

application(s)

agriculture
environmental

SMILES string

CN\C=N\c1ccc(C)cc1C

InChI

1S/C10H14N2.ClH/c1-8-4-5-10(9(2)6-8)12-7-11-3;/h4-7H,1-3H3,(H,11,12);1H

InChI key

VXSNJXDZTGFDMB-UHFFFAOYSA-N

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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M A Pass et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 99(1-2), 169-172 (1991-01-01)
1. Amitraz was rapidly metabolised to BTS27271 after intravenous administration to sheep. 2. Amitraz and BTS27271 had significant H1-histamine antagonist activity on isolated guinea-pig ileum. BTS27271 was approximately 3.3 times as potent as amitraz. 3. Intravenous injection of amitraz and
E A Abu-Basha et al.
Metabolism: clinical and experimental, 48(11), 1461-1469 (1999-12-03)
The study purpose was to investigate the direct effect of amitraz, a formamidine insecticide/acaricide, and its active metabolite BTS 27271 on insulin and glucagon secretion from the perfused rat pancreas. Amitraz and BTS 27271 (0.01, 0.1, 1, and 10 micromol/L)
Metabolic conversion of N'-(2,4-dimethylphenyl)-N-methylformamidine pesticide and the analysis of the metabolites.
Z Naikai et al.
Bulletin of environmental contamination and toxicology, 65(1), 22-27 (2000-06-30)
V C Ravikumar et al.
Toxicology, 27(1), 71-80 (1983-05-01)
The mammalian neuromuscular toxicity of N'-(2,4-xylyl)-N-methyl formamidine hydrochloride (U-40481A) was evaluated by programmed screening. The LD50 for mice, determined 48 h after single, subcutaneous (s.c.) injections, was 107 mg/kg body wt. Acute toxicity signs included abnormal gait, hindlimb hyperextension, transient
Carmen Ferrer et al.
Journal of AOAC International, 93(2), 380-388 (2010-05-20)
This paper compares the performance of the three most widely employed multiresidue methods [quick, easy, cheap, effective, rugged, and safe (QuEChERS), mini-Luke, and ethyl acetate] currently used for the determination of amitraz residues in fruits. A fast and differentiated analysis
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