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Merck
CN

32154

Buparvaquone

VETRANAL®, analytical standard

Synonym(s):

2-[(4-tert-Butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone, 2-[[4-(1,1-Dimethylethyl)cyclohexyl]methyl]-3-hydroxy-1,4-naphthalenedione

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About This Item

Empirical Formula (Hill Notation):
C21H26O3
CAS Number:
88426-33-9
Molecular Weight:
326.43
NACRES:
NA.24
PubChem Substance ID:
329754074
UNSPSC Code:
41116107
MDL number:
MFCD01712789

Key Documents

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InChI

1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3

SMILES string

CC(C)(C)C1CCC(CC1)CC2=C(O)C(=O)c3ccccc3C2=O

InChI key

KLLIVCPQDTYMLC-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6451
BCCJ1444
BCCJ1032
BCCG7901
BCCB5496

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H A Mbwambo et al.
Veterinary parasitology, 139(1-3), 67-73 (2006-03-29)
Evaluation trials of the efficacy of buparvaquone (BUTA-kel KELA Laboratoria, N.V. Belgium), as a treatment of field cases of Theileria parva infection (East Coast fever - ECF) were carried out on 63 cattle in the peri-urban of Dar Es Salaam
Norma Hernández-Trejo et al.
Journal of drug targeting, 13(8-9), 499-507 (2005-12-08)
The poorly soluble drug buparvaquone is proposed as an alternative treatment of Pneumocystis carinii pneumonia (PCP) lung infections. Physically stable nanosuspensions were formulated in order to deliver the drug at the site of infection using nebulization. The aerosolization characteristics of
Gantala Venkatesh et al.
Journal of pharmaceutical and biomedical analysis, 43(4), 1546-1551 (2006-12-13)
A simple, sensitive and specific reversed phase high performance liquid chromatographic (RP-HPLC) method with UV detection at 251 nm was developed for simultaneous quantitation of buparvaquone (BPQ), atenolol, propranolol, quinidine and verapamil. The method was applicable in rat in situ
D Haller et al.
Oncogene, 29(21), 3079-3086 (2010-03-09)
The function of the p53 protein as the central effector molecule of the p53 apoptotic pathway was investigated in a reversible model of epigenetic transformation. The infection of bovine leukocytes by the intracellular protozoan parasite Theileria annulata results in parasite-dependent
M Gwamaka et al.
The Onderstepoort journal of veterinary research, 71(2), 119-128 (2004-09-18)
The effects of dexamethasone and promethazine on the amelioration of pulmonary oedema in East Coast fever were investigated. The clinical effects of these drugs were further investigated when used in conjunction with the antitheilerial drug, buparvaquone. In the first experiment
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