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Merck
CN

32142

Pirbuterol acetate

VETRANAL®, analytical standard

Synonym(s):

(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt, 6-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate

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About This Item

Empirical Formula (Hill Notation):
C12H20N2O3 · C2H4O2
CAS Number:
65652-44-0
Molecular Weight:
300.35
PubChem Substance ID:
329754063
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
265-862-4
MDL number:
MFCD07773091
Beilstein/REAXYS Number:
13318829

Key Documents

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SMILES string

N(C(C)(C)C)CC(O)c1nc(c(cc1)O)CO.OC(=O)C

InChI

1S/C12H20N2O3.C2H4O2/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8;1-2(3)4/h4-5,11,13,15-17H,6-7H2,1-3H3;1H3,(H,3,4)

InChI key

QSXMZJGGEWYVCN-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Gene Information

human ... ADRB2(154)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL2488
BCCH8808
BCCH6973
BCBW8968
BCBS4084V

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P C Langley
Clinical therapeutics, 21(1), 236-253 (1999-03-25)
This paper reviews the impact of the use of technologically dissimilar beta-agonist aerosols--the Maxair Autohaler (pirbuterol acetate) breath-actuated aerosol and the traditional albuterol press-and-breathe inhaler-on the treatment costs of asthma. If, as clinical evidence would suggest, the breath-actuated aerosol is
N E Robinson et al.
Equine veterinary journal, 32(5), 393-400 (2000-10-19)
During a trial to determine the dose response to the beta2-adrenergic agonist pirbuterol, we judged the severity of airway obstruction by use of a clinical scoring system and compared this to objective data obtained by quantitative measures of lung function.
J S Kelloway et al.
Managed care interface, 10(9), 99-107 (1997-08-05)
Managed care plans evaluate therapeutic alternatives to identify the most cost-effective medications for asthma. Three hundred one patients with asthma were randomized to receive the beta-agonist pirbuterol from either a manually operated metered dose inhaler (MDI) or a breath-actuated inhaler
The use of two inhaled beta agonists for the treatment of COPD: a summary of European data.
K Holten et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 30(2), 123-126 (1993-01-01)
Paradoxical asthma hazard of short-acting beta2-agonists.
M J Seed et al.
Allergy, 63(2), 241-241 (2007-11-22)
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