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32087

Supelco

Cylindrospermopsin solution

10 μg/mL in H2O, PESTANAL®, analytical standard

Synonym(s):

6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione

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About This Item

Empirical Formula (Hill Notation):
C15H21N5O7S
CAS Number:
143545-90-8
Molecular Weight:
415.42
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

10 μg/mL in H2O

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

C[C@H]1[C@H](C[C@@H]2C[C@@H](N=C3NC[C@H]1N23)[C@@H](O)C4=CC(=O)NC(=O)N4)OS(O)(=O)=O

InChI

1S/C15H21N5O7S/c1-6-10-5-16-14-17-8(13(22)9-4-12(21)19-15(23)18-9)2-7(20(10)14)3-11(6)27-28(24,25)26/h4,6-8,10-11,13,22H,2-3,5H2,1H3,(H,16,17)(H,24,25,26)(H2,18,19,21,23)/t6-,7+,8-,10-,11+,13+/m1/s1

InChI key

LHJPHMKIGRLKDR-YUQKHPEDSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9813
BCCK5291
BCCJ1202
BCCH2167
BCCG5362

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J S Metcalf et al.
The Science of the total environment, 421-422, 118-123 (2012-03-01)
There have been few studies concerning cyanotoxins in desert environments, compared with the multitude of studies of cyanotoxins in aquatic environments. However, cyanobacteria are important primary producers in desert environments, where after seasonal rains they can grow rapidly both stabilising
V R Oliveira et al.
Toxicon : official journal of the International Society on Toxinology, 60(5), 764-772 (2012-07-04)
Cylindrospermopsin is a cyanobacterial toxin of increasing environmental importance, as it can lead to disease if orally or intravenously absorbed. However, its in vivo lung impairment has not been documented. Thus, we aimed at verifying whether cylindrospermopsin can induce lung injury
Barbara Poniedziałek et al.
Environmental toxicology and pharmacology, 34(3), 651-660 (2012-09-19)
Cylindrospermopsin (CYN) is a secondary metabolite produced by several cyanobacteria species. Its potential effect on human health includes liver, kidneys, lungs, spleen and intestine injuries. CYN can be cyto- and genotoxic to a variety of cell types. Occurrence and expansion
Remedios Guzmán-Guillén et al.
Environmental toxicology and chemistry, 31(10), 2233-2238 (2012-07-25)
A new method for determining dissolved cylindrospermopsin (CYN) in waters using solid-phase extraction (SPE) with graphitized carbon cartridges and quantification by liquid chromatography coupled with tandem mass spectrometry is described and discussed. The method has been suitably validated: the linear
Henar López-Alonso et al.
Chemical research in toxicology, 26(2), 203-212 (2012-12-29)
The increasing presence of cyanotoxin producers in several regions of the world is hazardous for humans and animals. Cylindrospermopsin (CYN) is nowadays recognized as a widely distributed freshwater cyanobacterial toxin. This toxin has been shown to induce protein synthesis inhibition
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