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Merck
CN

32053

Bronopol

PESTANAL®, analytical standard

Synonym(s):

2-Bromo-2-nitro-1,3-propanediol, BNPD, BNPK, Bronopol

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About This Item

Linear Formula:
HOCH2C(Br)(NO2)CH2OH
CAS Number:
Molecular Weight:
199.99
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-143-0
Beilstein/REAXYS Number:
1705868
MDL number:
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InChI

1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2

InChI key

LVDKZNITIUWNER-UHFFFAOYSA-N

SMILES string

OCC(Br)(CO)[N+]([O-])=O

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

130-133 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

General description

Bronopol is a broad-spectrum antibacterial agent. It is mostly used as a preservative in cosmetic, toiletry etc. It is also used in aerosol formulations.1

Application

Bronopol has been used as reference standard in ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (UPLC-ICP-MS) method for determination of bromine containing preservatives from cosmetic products.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

农药列管产品
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Andrew P Shinn et al.
Veterinary parasitology, 186(3-4), 229-236 (2011-12-14)
Pyceze™ (Novartis Animal Vaccines Ltd.) is licensed as a veterinary medicine to treat fungal infections in salmon, trout and their eggs. The active ingredient is bronopol, which due to its broad-spectrum activity has the potential to be an effective treatment
Ahmad Asadinezhad et al.
Colloids and surfaces. B, Biointerfaces, 77(2), 246-256 (2010-03-02)
Medical-grade polyvinyl chloride was surface modified by a multistep physicochemical approach to improve bacterial adhesion prevention properties. This was fulfilled via surface activation by diffuse coplanar surface barrier discharge plasma followed by radical graft copolymerization of acrylic acid through surface-initiated
M Matczuk et al.
International journal of cosmetic science, 34(5), 451-457 (2012-05-23)
Bronopol (2-bromo-2-nitropropane-1,3-diol) is used as preservative in cosmetic industry. Its main role in commercial products consists in protection of the cosmetic composition stability by inhibiting the development of micro-organisms. Unfortunately, preservatives can also undergo the degradation processes. The aim of
D Sierra et al.
Journal of dairy science, 92(10), 4841-4845 (2009-09-19)
This study was designed to evaluate the effects of different storage conditions on total bacterial count (TBC) determinations made in goat bulk tank milk using an automated flow cytometry method. The storage conditions tested were storage temperature (refrigeration at 4
Na Cui et al.
Environmental pollution (Barking, Essex : 1987), 159(2), 609-615 (2010-11-03)
Transformation products usually differ in environmental behaviors and toxicological properties from the parent contaminants, and probably cause potential risks to the environment. Toxicity evolution of a labile preservative, bronopol, upon primary aquatic degradation processes was investigated. Bronopol rapidly hydrolyzed in

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