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Sigma-Aldrich

1,10-Phenanthroline monohydrate

ACS reagent, 99%

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Synonym(s):
o-Phenanthroline monohydrate
Empirical Formula (Hill Notation):
C12H8N2 · H2O
CAS Number:
5144-89-8
Molecular Weight:
198.22
Beilstein:
4008096
EC Number:
200-629-2
MDL number:
MFCD00149973
UNSPSC Code:
12352100
PubChem Substance ID:
24859241
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

Assay

99%

technique(s)

titration: suitable

mp

100-104 °C (lit.)

suitability

passes test for determination of iron
passes test for redox indicator

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

Gene Information

human ... FNTA(2339)

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Application

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt (III) and iron (II) with 1, 10-phenanthroline and 2, 2'-bipyridine.
Carter MT, et al.
Journal of the American Chemical Society, 111(24), 8901-8911 (1989)
Photophysics and photochemistry of aromatic nitrogen heterocycles. Fluorescence from 2, 2'-bipyridine and 1, 10-phenanthroline.
Henry MS & Hoffman MZ.
The Journal of Physical Chemistry, 83(5), 618-625 (1979)
Bhumi Parikh et al.
Journal of food science and technology, 55(4), 1499-1507 (2018-04-03)
Pulses are valued for their protein content and are good source of bioactive phytochemicals. The objectives of this study were to estimate total phenolic content (TPC), flavonoid content and total antioxidant capacity (TAC) through six different assay methods from twenty
Khei Yan Lee et al.
Dalton transactions (Cambridge, England : 2003), 48(15), 4987-4999 (2019-03-28)
Chiral enantiomers [Cu(phen)(l-ser)(H2O)]NO31 and [Cu(phen)(d-ser)(H2O)]NO32 (ser = serinato) underwent aldol-type condensation with formaldehyde, with retention of chirality, to yield their respective enantiomeric ternary copper(ii) complexes, viz. l- and d-[Cu(phen)(OCA)(H2O)]NO3·xH2O (3 and 4; phen = 1,10-phenanthroline; OCA = oxazolidine-4-carboxylate; x =
Slađana Strmečki et al.
Analytica chimica acta, 955, 108-115 (2017-01-16)
Glycosylation of proteins plays an important role in health and diseases. At present new simple and inexpensive methods of glycoprotein analysis are sought. We developed a monoclonal antibody Manost 2.1 in mice after immunization with the adduct of mannan with
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