317802
4-(4-Isothiocyanatophenylazo)-N,N-dimethylaniline
97%
Synonym(s):
4-(Dimethylamino)azobenzene-4′-isothiocyanate, DABITC
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About This Item
Linear Formula:
SCNC6H4N=NC6H4N(CH3)2
CAS Number:
Molecular Weight:
282.36
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
231-521-3
Beilstein/REAXYS Number:
752568
MDL number:
InChI key
OSWZKAVBSQAVFI-ISLYRVAYSA-N
InChI
1S/C15H14N4S/c1-19(2)15-9-7-14(8-10-15)18-17-13-5-3-12(4-6-13)16-11-20/h3-10H,1-2H3/b18-17+
SMILES string
CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)N=C=S
assay
97%
form
crystals
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Related Categories
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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P M Fischer et al.
Analytical biochemistry, 177(1), 46-49 (1989-02-15)
A single-column high-performance liquid chromatographic separation of 4-N,N-dimethylaminoazobenzene 4'-thiohydantoin amino acid derivatives, generated during polypeptide sequence analysis by the 4-N,N-dimethylaminoazobenzene 4'-isothiocyanate/phenylisothiocyanate double coupling technique, is described. Recovery of the serine and threonine derivatives was improved by substituting boron trifluoride-diethyl etherate
R Aebersold et al.
Analytical biochemistry, 136(2), 465-469 (1984-02-01)
Proteins and polypeptides are derivatized with dimethylaminoazobenzene isothiocyanate (DABITC) before their separation on sodium dodecyl sulfate-polyacrylamide gels. DABITC-derivatized proteins are detected visually in the picomole range without further staining and destaining procedures. The recovered colored protein can also be used
A S Babu et al.
Toxicon : official journal of the International Society on Toxinology, 29(10), 1251-1262 (1991-01-01)
The effects of chemical modification with 4-NN-dimethyl amino azo benzene-4'-isothiocyanate on various biological activities of phospholipases A2, NN-XIII-PLA2 from Naja naja naja and VRV-PL-VIIIa from Vipera russelli snake venoms were investigated. Modification of the enzymes resulted in significant reduction of
I Jelesarov et al.
European journal of biochemistry, 216(1), 57-66 (1993-08-15)
The chloroplast enzyme ferredoxin: NADP+ reductase (FNR) catalyzes the reduction of NADP+ by ferredoxin (Fd). FNR and Fd form a 1:1 complex that is stabilized by electrostatic interactions between acidic residues of Fd and basic residues of FNR. To localize
A Wawrzynów et al.
Biochimica et biophysica acta, 1203(1), 60-70 (1993-11-10)
The Ca(2+)-ATPase protein of rabbit skeletal muscle sarcoplasmic reticulum is a single polypeptide chain of 1001 amino-acid residues. Among these residues are 24 Cys, 9 of which have previously been shown to be accessible to one or more thiol-specific reagents.
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