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Dimetridazole

VETRANAL®, analytical standard

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Synonym(s):
1,2-Dimethyl-5-nitroimidazole
Empirical Formula (Hill Notation):
C5H7N3O2
CAS Number:
551-92-8
Molecular Weight:
141.13
Beilstein:
130665
EC Number:
209-001-2
MDL number:
MFCD00047046
UNSPSC Code:
41116107
PubChem Substance ID:
329753891
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ncc(n1C)[N+]([O-])=O

InChI

1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3

InChI key

IBXPYPUJPLLOIN-UHFFFAOYSA-N

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General description

Dimetridazole (DMZ) is a 5-nitroimidazole type veterinary drug mostly used for treating infections caused by bacteria and protozoa. These infections can be frequently seen in the poultry industry.

Application

Dimetridazole has been used as reference standard for determination of DMZ concentration from poultry muscles, porcine kidney and liver, and chicken liver tissues using gas chromatography–electron capture negative ionization mass spectrometry (GC–ECNI-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of dimetridazole and metronidazole in poultry and porcine tissues by gas chromatography?electron capture negative ionization mass spectrometry.
Ho, Clare, et al.
Analytica Chimica Acta, 530.1, 23-31 (2005)
M Sánchez-Polo et al.
Water research, 43(16), 4028-4036 (2009-06-23)
The main objectives of this study were: (1) to investigate the decomposition and mineralization of nitroimidazoles (Metronidazole [MNZ], Dimetridazole [DMZ], and Tinidazole [TNZ]) in waste and drinking water using gamma irradiation; (2) to study the decomposition kinetics of these nitroimidazoles;
M G Müller et al.
Veterinary parasitology, 152(1-2), 67-78 (2008-01-02)
Four falcons from a private collection of 137 falcons in Abu Dhabi (UAE) died suddenly in summer 2005. In order to screen for a possible disease among the remaining falcons in the aviary, all other birds were caught, examined and
Jianzhong Shen et al.
Journal of AOAC International, 86(3), 505-509 (2003-07-11)
A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the
M-P Callait-Cardinal et al.
The Veterinary record, 161(17), 581-585 (2007-10-30)
Between April 2003 and March 2005, 113 outbreaks of histomonosis were recorded in standard turkey farms in France, and 15 cases were recorded in turkey breeding centres. Most of the cases were in north-west France, the principal farming area for
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