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Supelco

2-Naphthylamine

analytical standard

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Synonym(s):
β-Naphthylamine, 2-Aminonaphthalene
Linear Formula:
C10H7NH2
CAS Number:
91-59-8
Molecular Weight:
143.19
Beilstein:
3939429
EC Number:
202-080-4
MDL number:
MFCD00004112
UNSPSC Code:
41116107
PubChem Substance ID:
329753849
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

306 °C (lit.)

mp

111-113 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

Nc1ccc2ccccc2c1

InChI

1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

InChI key

JBIJLHTVPXGSAM-UHFFFAOYSA-N

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General description

2-Naphthylamine is a carcinogenic aromatic amine which induces tumor in urinary bladder.

Application

2-Naphthylamine has been used as reference standard during isolation and identification of urinary metabolites using preparative thin-layer chromatography and gas-liquid chromatography/mass spectral analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

Signal Word

Danger

Hazard Statements

H302,H350,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine.
Kadlubar FF
Carcinogenesis, 2(5), 467-470 (1981)
Metabolic conversion of 1-and 2-nitronaphthalene to 1-and 2-naphthylamine in the rat.
Johnson, Dale E., and Herbert H. Cornish.
Toxicology and Applied Pharmacology, 46.3, 549-553 (1978)
Dylan M Owen et al.
Nature communications, 3, 1256-1256 (2012-12-06)
Lipid microdomains are postulated to regulate many membrane-associated processes but have remained highly controversial. Here we provide the first direct evidence that the plasma membrane of intact, live cells is comprised of a sub-resolution mixture of approximately 76% ordered and
Weimei Sun et al.
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Inhibition of the serine protease enteropeptidase (EP) opens a new avenue to the discovery of chemotherapeutics for the treatment of metabolic diseases. Camostat has been used clinically for treating chronic pancreatitis in Japan; however, the mechanistic basis of the observed
Carlos de la Haba et al.
Biochimica et biophysica acta, 1828(2), 357-364 (2012-09-04)
Plasma membrane is one of the preferential targets of reactive oxygen species which cause lipid peroxidation. This process modifies membrane properties such as membrane fluidity, a very important physical feature known to modulate membrane protein localization and function. The aim
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