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309052

Sigma-Aldrich

Quinoline Yellow

Mixture of the mono- and disulfonic acids of Quinoline Yellow

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Synonym(s):
Acid Yellow 3
CAS Number:
8004-92-0
Colour Index Number:
47005
UNSPSC Code:
12171500
NACRES:
NA.47

Quality Level

200

form

powder

technique(s)

titration: suitable

solubility

H2O: soluble
spirit: soluble (23,413-3)

λmax

412 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

InChI

1S/C18H11NO8S2.2Na/c20-17-11-3-1-2-4-12(11)18(21)15(17)13-6-5-9-7-10(28(22,23)24)8-14(16(9)19-13)29(25,26)27;;/h1-8,15H,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2

InChI key

FZUOVNMHEAPVBW-UHFFFAOYSA-L

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General description

Quinoline Yellow is a yellow, water-soluble, anionic quinophthalone dye. This synthetic dye is generally used as a food additive. Its applications are also seen in the cosmetic and pharmaceutical industries. It is a chinophthalon derivative applied in the compositions of skin, lips, or body cosmetics.Studies show that Quinoline Yellow is not genotoxic or carcinogenic. It is considered to be safe for human health.

Application

Quinoline Yellow has been used as an absorber for the fabrication of the micro-phantoms.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Methyldopa-induced skin rash.
G Gidseg
Southern medical journal, 79(3), 389-389 (1986-03-01)
A L Goldberg
Journal - Association of Official Analytical Chemists, 68(3), 477-479 (1985-05-01)
A sensitive, reproducible method that uses an Extrelut QE column and liquid chromatography (LC) in the reverse phase mode is described for the determination of 2-(2-quinolinyl)-1H-indene-1,3-[2H]-dione and other organic-soluble matter found in D&C Yellow No. 10. With this method the
Sensitization potentials of D & C Yellow No. 10 and D & C Yellow No. 11 dyes.
J E Weaver
Journal of the American Academy of Dermatology, 9(4), 605-606 (1983-10-01)
Adrian Weisz et al.
Journal of mass spectrometry : JMS, 37(10), 1025-1033 (2002-10-11)
Several positional isomers of 2-(2-quinolinyl)-1H-indene-1,3(2H)-dione mono- and disulfonic acids prepared as reference materials for development of analytical methods involved in FDA certification of D&C Yellow No. 10 (Quinoline Yellow) were found consistently to show [MH + 14](+) ions when their
Adrian Weisz et al.
Journal of chromatography. A, 1216(19), 4161-4168 (2009-03-14)
Four positionally isomeric 2-(2-quinolinyl)-1H-indene-1,3(2H)-dionedisulfonic acids (SA) and one triSA, components of the color additive Quinoline Yellow (QY, Color Index No. 47005), were isolated from the dye mixture by affinity-ligand pH-zone-refining counter-current chromatography (CCC) through complementary use of ion-exchange and ion-pair
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