301310
2-Ethyl-2-thiopseudourea hydrobromide
98%
Synonym(s):
S-Ethylisothiourea hydrobromide
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About This Item
Linear Formula:
C2H5SC(=NH)NH2 · HBr
CAS Number:
Molecular Weight:
185.09
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
SMILES string
Br.CCSC(N)=N
InChI key
SWXXKWPYNMZFTE-UHFFFAOYSA-N
assay
98%
form
powder or crystals
mp
88-90 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Application
Reagent used in the synthesis of pyrimidines.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Barbara T Alexander et al.
Hypertension (Dallas, Tex. : 1979), 39(2 Pt 2), 586-590 (2002-03-08)
Acute, nonselective nitric oxide synthase inhibition in the pregnant rat decreases glomerular filtration rate and renal plasma flow, suggesting a role for nitric oxide in mediating renal vasodilation during pregnancy. As mid-gestation in the rat is associated with a significant
A L Bardell et al.
The Journal of pharmacology and experimental therapeutics, 296(2), 252-259 (2001-02-13)
Experiments were performed to investigate whether nitric-oxide synthase (NOS) activity can be detected in vascular smooth muscle (VSM) from 12- to 14-week streptozotocin (STZ)-diabetic rats. Concentration-response curves to norepinephrine (NE) of superior mesenteric arteries from diabetic and age- and gender-matched
E Alhan et al.
The European journal of surgery = Acta chirurgica, 164(9), 697-702 (1998-09-05)
To investigate the effects of the constitutive nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-Name) and the inducible NO synthase inhibitor amino ethyl-isothiourea (AE-ITU) on acute necrotising pancreatitis (ANP) in rats. Laboratory study. Medical school, Turkey. Morbidity, mortality, effects
Mihoko N Nakashima et al.
Journal of pharmacological sciences, 91(1), 47-52 (2003-04-11)
The possible role of nitric oxide (NO) in anxiety following transient cerebral ischemia by a 10-min bilateral carotid occlusion was examined in mice. Two days after the ischemia, mice showed a significant decrease in time spent on the open arms
R L Rairigh et al.
The Journal of clinical investigation, 101(1), 15-21 (1998-02-14)
Nitric oxide (NO) produced by NO synthase (NOS) modulates fetal pulmonary vascular tone and contributes to the fall in pulmonary vascular resistance (PVR) at birth. Although the inducible (type II) NOS isoform is present in human and rat fetal lungs
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