301310
2-Ethyl-2-thiopseudourea hydrobromide
98%
Synonym(s):
S-Ethylisothiourea hydrobromide
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All Photos(3)
About This Item
Linear Formula:
C2H5SC(=NH)NH2 · HBr
CAS Number:
Molecular Weight:
185.09
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
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Assay
98%
form
powder or crystals
mp
88-90 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Br.CCSC(N)=N
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
InChI key
SWXXKWPYNMZFTE-UHFFFAOYSA-N
Application
Reagent used in the synthesis of pyrimidines.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Barbara T Alexander et al.
Hypertension (Dallas, Tex. : 1979), 39(2 Pt 2), 586-590 (2002-03-08)
Acute, nonselective nitric oxide synthase inhibition in the pregnant rat decreases glomerular filtration rate and renal plasma flow, suggesting a role for nitric oxide in mediating renal vasodilation during pregnancy. As mid-gestation in the rat is associated with a significant
A L Bardell et al.
The Journal of pharmacology and experimental therapeutics, 296(2), 252-259 (2001-02-13)
Experiments were performed to investigate whether nitric-oxide synthase (NOS) activity can be detected in vascular smooth muscle (VSM) from 12- to 14-week streptozotocin (STZ)-diabetic rats. Concentration-response curves to norepinephrine (NE) of superior mesenteric arteries from diabetic and age- and gender-matched
Claus Martin et al.
Cardiovascular research, 74(1), 46-55 (2007-01-30)
Nitric oxide (NO) synthesis by NO synthases (NOS) requires oxygen. However, although counterintuitive, NO synthesis is increased in ischemic myocardium. Accordingly, mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental
M Booke et al.
Critical care medicine, 27(1), 162-167 (1999-02-06)
To investigate the effects of S-ethylisothiourea (S-EITU) on hemodynamics, oxygen transport, and regional blood flow in healthy and septic sheep. Prospective, randomized, controlled experimental study with repeated measures. Investigational intensive care unit at a university medical center. Eleven healthy, female
F Squadrito et al.
British journal of pharmacology, 119(1), 23-28 (1996-09-01)
1. The aim of this study was to compare the effects of an intravenous infusion of a potent and non selective nitric oxide synthase inhibitor S-ethylisothiourea (Ethyl-TU) with that of a nitric oxide (NO) donor on the pathological sequelae associated
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