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27001-M

Sigma-Aldrich

Formic acid

puriss., meets analytical specifications of DAC, FCC, 98.0-100%

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Linear Formula:
HCOOH
CAS Number:
64-18-6
Molecular Weight:
46.03
Beilstein:
1209246
EC Number:
200-579-1
MDL number:
MFCD00003297
UNSPSC Code:
12352106
PubChem Substance ID:
329752893
NACRES:
NA.21

vapor density

1.6 (vs air)

Quality Level

100

vapor pressure

44.8 mmHg ( 20 °C)

grade

puriss.

Assay

98.0-100%

form

liquid

autoignition temp.

1004 °F

quality

meets analytical specifications of DAC, FCC

expl. lim.

57 %

impurities

≤0.001% heavy metals (as Pb)
≤0.05% acetic acid (GC)

evapn. residue

≤0.005%

refractive index

n20/D 1.370 (lit.)

pH

2.2 (20 °C, 2.2 g/L)

bp

100-101 °C (lit.)

mp

8.2-8.4 °C (lit.)

density

1.22 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 ppm
sulfate (SO42-): ≤40 ppm
sulfite (SO32-): in accordance

cation traces

Fe: ≤0.001%
heavy metals (as Pb): ≤0.001%

SMILES string

OC=O

InChI

1S/CH2O2/c2-1-3/h1H,(H,2,3)

InChI key

BDAGIHXWWSANSR-UHFFFAOYSA-N

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Application

  • Determination of Cotinine and 3-hydroxynicotinine in Human Serum: This study presents a method for detecting nicotine metabolites in human serum using liquid chromatography-tandem mass spectrometry, where formic acid is used to aid in the extraction and detection process (Wang et al., 2024).
  • Quantification of Antiretrovirals in Human Tissues: Focuses on a method for quantifying antiretrovirals in tissues using ultra-high performance liquid chromatography-tandem mass spectrometry, where formic acid may enhance the analysis (West et al., 2024).
  • Redox Regulation of Ni Hydroxides: This research into the electro-refinery of biomass-derived polyols may involve formic acid in the preparation of samples or in the electrolyte solutions used (Gui et al., 2024).
  • Volatile Fatty Acids in Biological Specimens: Discusses a technique for determining volatile fatty acids in various biological samples using HPLC-MS/MS with a low-temperature derivatisation method that likely involves formic acid (Li et al., 2024).

Signal Word

Danger

Hazard Statements

H226,H302,H314,H331

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Supplementary Hazards

EUH071

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

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M Athar Masood et al.
Basic & clinical pharmacology & toxicology, 127(6), 533-550 (2020-11-03)
Urine drug testing (UDT) is an important analytical/bio-analytical technique that has inevitably become an integral and vital part of a testing programme for diagnostic purposes. This manuscript presents a tailor-made LC-MS/MS quantitative assay method development and validation for a custom
Heng Lu et al.
Cell communication insights, 5, 1-7 (2014-05-20)
Protein-protein interactions play a pivotal role in both inter- and intra-cellular signaling. Identification of signaling protein complexes can thus shed important new insights into cell communications. We developed a parallel affinity precipitation protocol to overcome the disadvantages of the tandem

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