Skip to Content
Merck
CN
All Photos(5)

Documents

Safety Information

252360

Sigma-Aldrich

Morpholine

ACS reagent, ≥99.0%

Synonym(s):

Tetrahydro-1,4-oxazine

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

Empirical Formula (Hill Notation):
C4H9NO
CAS Number:
110-91-8
Molecular Weight:
87.12
Beilstein:
102549
EC Number:
203-815-1
MDL number:
MFCD00005972
UNSPSC Code:
12352100
eCl@ss:
39162409
PubChem Substance ID:
24855203
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

vapor density

3 (vs air)

vapor pressure

31 mmHg ( 38 °C)
7 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

590 °F

expl. lim.

10.8 %

color

APHA: ≤15

refractive index

n20/D 1.454 (lit.)

bp

126.0-130.0 °C
129 °C (lit.)

mp

−7-−5 °C (lit.)

density

0.996 g/mL at 25 °C (lit.)

SMILES string

C1COCCN1

InChI

1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2

InChI key

YNAVUWVOSKDBBP-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Morpholine may be used in the preparation of derivatives such as 4-benzoyloxymorpholine and 1-morpholinopropan-1-one. It may also be used in the preparation of (S)-3,3′-bis-morpholinomethyl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-bi-2-naphthol, a bifunctional chiral catalyst for asymmetric synthesis. As a base, morpholine can be used in the preparation of 1,3-disubstituted allenes from terminal alkynes and aldehydes.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - Skin Corr. 1B

WGK

WGK 1

Flash Point(F)

87.8 °F

Flash Point(C)

31 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of acylsilanes from morpholine amides. Synthesis of 1-(dimethyl(phenyl)silyl)propan-1-one
Lettan II RB, et al.
Organic Syntheses, 84, 22-22 (2007)
Factors influencing the rate of formation of nitrosomorpholine from morpholine and nitrite: acceleration by thiocyanate and other anions.
T Y Fan et al.
Journal of agricultural and food chemistry, 21(2), 237-240 (1973-03-01)
Copper-catalyzed electrophilic amination of diorganozinc reagents: 4-phenylmorpholine
Berman AM and Johnson JS
Organic Syntheses, 83, 31-31 (2006)
Preparation of (S)-3,3'-bis-morpholinomethyl-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol
MTurlington M and Pu L
Organic Syntheses, 87, 59-59 (2010)
First telomerisation of piperylene with morpholine using palladium-carbene catalysts.
Neubert P, et al.
Catalysis Communications, 77, 70-74 (2016)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service