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Key Documents

Safety Information

19740

Sigma-Aldrich

tert-Butyl carbazate

purum, ≥98.0% (GC)

Synonym(s):

tert-Butoxycarbonyl hydrazide, Boc-hydrazide

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About This Item

Linear Formula:
(CH3)3COCONHNH2
CAS Number:
Molecular Weight:
132.16
Beilstein:
1756967
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:

grade

purum

Assay

≥98.0% (GC)

bp

63-65 °C/0.1 mmHg (lit.)

mp

38-42 °C
39-42 °C (lit.)

application(s)

peptide synthesis

SMILES string

O=C(NN)OC(C)(C)C

InChI

1S/C5H12N2O2/c1-5(2,3)9-4(8)7-6/h6H2,1-3H3,(H,7,8)

InChI key

DKACXUFSLUYRFU-UHFFFAOYSA-N

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Other Notes

This product has been replaced by B91005-ALDRICH | tert-Butyl carbazate 98%
Starting material for preparing BOC-azide, a reagent to introduce the BOC amino protection; E. Wünsch in Houben-Weyl, Vol. 15/1, Synthese von grossen Peptiden, p. 112.; Reagent for the synthesis of sulfonic and carboxylic hydrazides

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Flam. Sol. 1

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

195.8 °F

Flash Point(C)

91 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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M.S. Gordon et al.
Synthesis, 244-244 (1980)
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The AAPS journal, 16(6), 1185-1193 (2014-09-07)
Presentation of antigen with immune stimulating "signal" has been a cornerstone of vaccine design for decades. Here, the antigen plus immune "signal" of vaccines is modified to produce antigen-specific immunotherapies (antigen-SITs) that can potentially reprogram the immune response toward tolerance

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