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19443

Supelco

Andrograpanin

analytical standard

Synonym(s):

3,14-Dideoxyandrographolide, 3-[2-[(1R,4aS,5R,8aS)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone, ent-19-Hydroxy-8(17),13-labdadien-16,15-olide

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About This Item

Empirical Formula (Hill Notation):
C20H30O3
CAS Number:
82209-74-3
Molecular Weight:
318.45
MDL number:
MFCD07778568
UNSPSC Code:
85151701
PubChem Substance ID:
329751877
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥95% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

C[C@@]1(CO)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12

InChI

1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1

InChI key

WKKBRRFSRMDTJB-JYBIWHBTSA-N

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General description

Andrograpanin, diterpene lactone is a hydrolysate drug used as anti-inflammatory agent. It is a minor compound of Andrographis paniculata. It has the potential to modulate the chemokine pathway and is used in anti-infectious function. It may be used in treating infections, inflammation, cold, fever and diarrhea.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT1948

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Jun Liu et al.
International immunopharmacology, 8(7), 951-958 (2008-05-20)
Andrographis paniculata Nees is an official herbal medicine for treatment of infection and inflammation in China. Andrograpanin, the one of diterpene lactones in A. paniculata, is a hydrolysate from neoandrographolide in vivo and in vitro. The goal of the present
Li-Li Ji et al.
Journal of cellular biochemistry, 95(5), 970-978 (2005-06-07)
Andrographis paniculata is a traditional Chinese medicine (TCM) that has been effectively used for treatment of infection, inflammation, cold, fever, and diarrhea in China. However, mechanism of its therapeutic function is not well known. In the current study, we showed

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