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Lactitol

analytical standard

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Synonym(s):
4-O-β-D-Galactopyranosyl-D-glucitol, D-Lactitol, E 966, Lactobiosit, Lactositol, no translation
Empirical Formula (Hill Notation):
C12H24O11
CAS Number:
585-86-4
Molecular Weight:
344.31
EC Number:
209-566-5
MDL number:
MFCD00079407
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥99.0% (HPLC)

optical activity

[α]/D 14.5±1.5°, c = 1 in H2O

shelf life

limited shelf life, expiry date on the label

impurities

≤6.0% water

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

InChI

1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2

InChI key

VQHSOMBJVWLPSR-UHFFFAOYSA-N

General description

Lactitol is an analog of the disaccharide alcohol, lactulose. It is used as a laxative in the treatment of constipation. This unabsorbable lactose derivative has attracted interest as a sweetener for low-calorie foods.

Application

Lactitol may be used as an analytical reference standard for the determination of the analyte in food products by ultra-performance liquid chromatography (UPLC) with an evaporative light scattering detector (ELSD) and high-pH anion-exchange chromatography with pulsed amperometric detection.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

涉药品监管产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lactitol: a review of its use in the treatment of constipation
Faruqui AA and Joshi C
International Journal of Recent Advances in Pharmaceutical Research, 2(1), 1-5 (2012)
Lactulose enhances neuroplasticity to improve cognitive function in early hepatic encephalopathy
Yang N, et al.
Neural Regeneration Research, 10(9), 1457-1457 (2015)
Separation and determination of alditols and sugars by high-pH anion-exchange chromatography with pulsed amperometric detection
Andersen R and S?rensen A
Journal of Chromatography A, 897(1-2), 195-204 (2000)
A rapid method for simultaneous quantification of 13 sugars and sugar alcohols in food products by UPLC-ELSD
Koh DW, et al.
Food Chemistry, 240(9), 694-700 (2018)
Lactitol
Zacharis, Christos
Sweeteners: Nutritional Aspects, Applications, and Production Technology, 10(9), 275-293 (2012)

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