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Safety Information

18951

Supelco

1-Naphthyl isothiocyanate

for HPLC derivatization, LiChropur™, ≥98.5% (HPLC and GC)

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About This Item

Linear Formula:
C10H7NCS
CAS Number:
551-06-4
Molecular Weight:
185.24
EC Number:
208-990-8
MDL number:
MFCD00003882
UNSPSC Code:
41116105
PubChem Substance ID:
329751761
NACRES:
NA.22

grade

for HPLC derivatization

Quality Level

100

Assay

≥98.5% (HPLC and GC)

form

solid

quality

LiChropur™

technique(s)

HPLC: suitable

mp

55.5-57 °C (lit.)

SMILES string

S=C=Nc1cccc2ccccc12

InChI

1S/C11H7NS/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-7H

InChI key

JBDOSUUXMYMWQH-UHFFFAOYSA-N

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7719
BCCF4405
BCBW8813
BCBW7587
BCBW0368

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Li-Li Ding et al.
Journal of ethnopharmacology, 140(2), 222-229 (2012-01-26)
Danning tablet, as a composite prescription of traditional Chinese medicine, has been used clinically to relieve liver and gallbladder diseases in China. However, the mechanisms involved are still unclear. The present investigation was designed to assess the effects and possible
N Mori et al.
Die Pharmazie, 65(7), 457-460 (2010-07-29)
The intestinal absorption of mizoribine, an imidazole nucleoside, is mediated by concentrative nucleoside transporter (CNT)1 and CNT2 in rat. Previously, bile and bile salts such as sodium glycocholate were found to suppress the intestinal absorption of mizoribine. In the present
Matthew Quinn et al.
American journal of physiology. Gastrointestinal and liver physiology, 302(1), G182-G193 (2011-10-08)
Cholestatic patients often present with clinical features suggestive of adrenal insufficiency. In the bile duct-ligated (BDL) model of cholestasis, the hypothalamic-pituitary-adrenal (HPA) axis is suppressed. The consequences of this suppression on cholangiocyte proliferation are unknown. We evaluated 1) HPA axis
John M Cullen et al.
Toxicologic pathology, 41(1), 7-17 (2012-08-14)
Depletion of Kupffer cells, known to modulate chemical-induced hepatocellular injury, has not been studied with regard to biliary epithelial injury. Here, the authors investigated the effect of Kupffer cell depletion by clodronate on the toxicity of alpha-naphthylisothiocyanate (ANIT), known to
Igor Sukhotnik et al.
Pediatric surgery international, 28(2), 161-169 (2011-10-13)
Progressive hyperbilirubinemia and end-stage liver failure are among the most serious complications of short bowel syndrome (SBS), representing the principle cause of death in a majority of fatal cases. In the current study, we examined the effects of alpha-naphthylisothiocyanate (ANIT)-induced
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