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Ipriflavone

analytical standard

Synonym(s):

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one, Ipriflavone

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About This Item

Empirical Formula (Hill Notation):
C18H16O3
CAS Number:
35212-22-7
Molecular Weight:
280.32
MDL number:
MFCD00221719
UNSPSC Code:
85151701
PubChem Substance ID:
329751252

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

116-120 °C (lit.)

format

neat

SMILES string

CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1

InChI

1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3

InChI key

SFBODOKJTYAUCM-UHFFFAOYSA-N

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General description

Ipriflavone, a flavonoid derivative of the natural isoflavone compound, plays a role in the mitochondrial phosphorylation and exhibits growth-promoting activity.

Application

Ipriflavone can be used as an analytical standard for the determination of the analyte in human and animal biological samples by liquid chromatography (LC) based methods.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Determination of ipriflavone and its synthetic impurities by high-performance liquid chromatography using diode-array detection
Sustacha K, et al.
Journal of Chromatography A, 719(1), 245-250 (1996)
Simultaneous determination of ipriflavone and its main metabolites M1 and M5 in human plasma by liquid chromatography with tandem mass spectrometry
Ji HY, et al.
Analytical Letters, 38(1), 99-110 (2005)
Hye J Chung et al.
The Journal of pharmacy and pharmacology, 58(4), 449-457 (2006-04-07)
In order to find out what types of the hepatic microsomal cytochrome P450 (CYP) isozymes are involved in the metabolism of ipriflavone, ipriflavone at a dose of 20 mg kg(-1) (or 15 mg kg(-1)) was infused in male Sprague-Dawley rats.
Disposition of ipriflavone (TC-80) in rats and dogs.
Yoshida K, et al.
Radioisotopes, 34(11), 618-623 (1985)
H J Chung et al.
Research in veterinary science, 85(1), 149-155 (2007-10-09)
It has been reported that ipriflavone was primarily metabolized via hepatic microsomal cytochrome P450 (CYP) 1A1/2 and 2C11 in rats, and the expression of hepatic CYP1A2 and 2C11 was not changed in rats with water deprivation for 72h compared to
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