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157775

Sigma-Aldrich

Phosphorus pentachloride

reagent grade, 95%

Synonym(s):

Phosphorus(V) chloride

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About This Item

Linear Formula:
PCl5
CAS Number:
Molecular Weight:
208.24
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

grade

reagent grade

Quality Level

vapor pressure

<1 mmHg ( 20 °C)

Assay

95%

form

powder

pH

1 (5 g/L)

mp

179-181 °C (subl.) (lit.)

SMILES string

ClP(Cl)(Cl)(Cl)Cl

InChI

1S/Cl5P/c1-6(2,3,4)5

InChI key

UHZYTMXLRWXGPK-UHFFFAOYSA-N

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General description

Phosphorus pentachloride is a light yellow colored phosphorous halide. It participates in the synthesis of thiazoline analogs.

Application

Phosphorus pentachloride may be used in the synthesis of following compounds:
  • benzenesulfonyl chloride
  • malonic dinitrile
  • aromatic sulfonyl chlorides

Phosphorus pentachloride may be used as halogenating reagent to convert any substituted aldehyde into the corresponding vinyl halide. It can also undergo reaction with ammonium chloride to yield linear phosphazenes and cyclophosphazenes.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT RE 2 Inhalation

Target Organs

Respiratory Tract

Supplementary Hazards

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Allcock H
Phosphorus-Nitrogen Compounds: Cyclic, Linear, and High Polymeric Systems (2012)
Ley.VS et al.
Comprehensive Organic Functional Group Transformations: Synthesis: carbon with two heteroatoms, each attached by a single bond (2005)
Ley.VS
Comprehensive Organic Functional Group Transformations II, 2 (1995)
Eagleson M.
Concise Encyclopedia Chemistry, 617-617 (1994)
Synthetic studies of thiazoline and thiazolidine-containing natural products-1. Phosphorus pentachloride-mediated thiazoline construction reaction.
Ino A and Murabayashi A.
Tetrahedron, 55(34), 10271-10282 (1999)

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