Skip to Content
Merck
CN

15269

N,O-Bis(trimethylsilyl)acetamide

derivatization grade (GC derivatization), LiChropur™, ≥98.5% (GC)

Synonym(s):

BSA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CH3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
10416-59-8
Molecular Weight:
203.43
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
329750807
EC Number:
233-892-7
Beilstein/REAXYS Number:
1306669
MDL number:
MFCD00008270

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N,O-Bis(trimethylsilyl)acetamide, derivatization grade (GC derivatization), LiChropur™, ≥98.5% (GC)

InChI key

SIOVKLKJSOKLIF-CMDGGOBGSA-N

InChI

1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3/b9-8+

SMILES string

C\C(O[Si](C)(C)C)=N/[Si](C)(C)C

grade

derivatization grade (GC derivatization)

assay

≥98.5% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.417 (lit.)
n20/D 1.417

bp

71-73 °C/35 mmHg (lit.)

density

0.832 g/mL at 20 °C (lit.)

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Learn more in the Product Information
Suitable for the derivatization of 2-amino-2-dexoxyhexoses, ecdysones, hexosamines in glycosaminoglycans, 18-hydroxycorticosteroids, 15-Oxo-prostaglandin F2α, prostaglandins A,B and E and F, F2α, prostaglandins and metabolites, prostaglandins Emetabolites, sugar phosphates, steroids and testosterone.

General description

N,O-Bis(trimethylsilyl)acetamide is an excellent silylation reagent. For some sterically hindered primary or secondary nitro compounds, N,O-bis(trimethylsilyl)acetamide and BSTFA achieve better results than normal silylation conditions.

Other Notes

Powerful silylating agent
Reagent for o-trimethylsilyl-aldono-1,4-lactones, trimethylsilyl and trimethylsilyl ether.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B

supp_hazards

EUH014

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

111.2 °F - closed cup

flash_point_c

44 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN2669
BCCL5983
BCCL8147
BCCK0041
BCCJ3420

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Houben-Weyl Methods of Molecular Transformations. Heteroatom Analogues of Aldehydes and Ketones.
Aggarwal VK
Science of Synthesis Knowledge Updates, 27, 593-594 (2014)
Analysis of the prostaglandins E by glass capillary gas chromatography with electron capture detection.
M Korteweg et al.
Prostaglandins, 13(6), 1221-1223 (1977-06-01)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
K. Blau et al.
Handbook of Derivatives for Chromatography (1993)
Anna Hjelm et al.
Applied and environmental microbiology, 81(2), 726-735 (2014-11-16)
Bacterial ghosts are empty cell envelopes of Gram-negative bacteria that can be used as vehicles for antigen delivery. Ghosts are generated by releasing the bacterial cytoplasmic contents through a channel in the cell envelope that is created by the controlled
View All Related Papers

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service