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Merck
CN

14089

Succinic anhydride

puriss., ≥99.0% (NT)

Synonym(s):

Dihydro-2,5-furandione

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About This Item

Empirical Formula (Hill Notation):
C4H4O3
CAS Number:
Molecular Weight:
100.07
EC Number:
203-570-0
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
108441
MDL number:
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InChI key

RINCXYDBBGOEEQ-UHFFFAOYSA-N

InChI

1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2

SMILES string

O=C1CCC(=O)O1

vapor density

3.5 (vs air)

vapor pressure

1 mmHg ( 92 °C)

grade

puriss.

assay

≥99.0% (NT)

bp

261 °C (lit.)

mp

118-120 °C

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

314.6 °F

flash_point_c

157 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Peisheng Xu et al.
Biomacromolecules, 11(9), 2352-2358 (2010-08-11)
Zwitterionic chitosan, a chitosan derivative with a unique pH-dependent charge profile, was employed to create a stealth coating on the cationic surface of drug carriers. Zwitterionic chitosans were synthesized by amidation of chitosan with succinic anhydride. The succinic anhydride-conjugated chitosan
Bingnan Han et al.
Journal of proteomics, 75(18), 5724-5733 (2012-07-31)
We report a mass spectrometry-based comparative "bottom up" proteomics approach that combines d(0)/d(4)-succinic anhydride labeling with commercially available hydrazine (Hz)-functionalized beads (Affi-gel Hz beads) for detection, identification and relative quantification of site-specific oxylipid modifications in biological matrices. We evaluated and
Jean-François Poulin et al.
International journal of pharmaceutics, 405(1-2), 47-54 (2010-12-07)
The use of succinylated β-lactoglobulin as a novel functional tablet excipient for the protection of probiotic bacteria against the adverse gastric conditions and their delivery in the intestine was studied. Tablets were produced by direct compression of a dry mixture
Romain Caillard et al.
International journal of pharmaceutics, 437(1-2), 130-136 (2012-08-01)
Succinylated β-lactoglobulin (S-β-lg) was previously shown to be efficient as new excipient for the formation of enteric tablets, suitable for several applications including probiotics delivery. This work investigates the mechanisms leading to S-β-lg tablets delayed release. Release kinetics were evaluated
Wenlian Zhu et al.
Magnetic resonance in medicine, 59(4), 679-685 (2008-02-28)
Pretargeting of receptors is a useful approach in molecular imaging and therapy to reduce background noise or toxicity and enhance selectivity. In this study a three-step pretargeting approach that includes a biotinylated antibody, avidin/streptavidin, and a biotinylated imaging agent is

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