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Merck
CN

11150

L-Asparagine

anhydrous, ≥99.0% (NT)

Synonym(s):

(S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide

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About This Item

Linear Formula:
H2NCOCH2CH(NH2)CO2H
CAS Number:
70-47-3
Molecular Weight:
132.12
EC Number:
200-735-9
UNSPSC Code:
12352200
MDL number:
MFCD00064401
Beilstein/REAXYS Number:
1723527

Key Documents

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InChI

1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1

InChI key

DCXYFEDJOCDNAF-REOHCLBHSA-N

SMILES string

N[C@@H](CC(N)=O)C(O)=O

assay

≥99.0% (NT)

optical activity

[α]20/D +35.0±0.5°, c = 5% in 5 M HCl

impurities

≤0.1% foreign amino acids

ign. residue

≤0.1% (as SO4)

mp

235 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤50 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Kira Ekberg et al.
The Journal of biological chemistry, 288(14), 9610-9618 (2013-02-20)
The minimal proton pumping machinery of the Arabidopsis thaliana P-type plasma membrane H(+)-ATPase isoform 2 (AHA2) consists of an aspartate residue serving as key proton donor/acceptor (Asp-684) and an arginine residue controlling the pKa of the aspartate. However, other important
Phuc Vinh Nguyen Lam et al.
Genomics, proteomics & bioinformatics, 11(2), 96-104 (2013-03-06)
The asparagine-X-serine/threonine (NXS/T) motif, where X is any amino acid except proline, is the consensus motif for N-linked glycosylation. Significant numbers of high-resolution crystal structures of glycosylated proteins allow us to carry out structural analysis of the N-linked glycosylation sites
Tatsuo Yanagisawa et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 1), 5-15 (2013-01-01)
Structures of Methanosarcina mazei pyrrolysyl-tRNA synthetase (PylRS) have been determined in a novel crystal form. The triclinic form crystals contained two PylRS dimers (four monomer molecules) in the asymmetric unit, in which the two subunits in one dimer each bind
Eliza A Ruben et al.
Biochemistry, 52(6), 1074-1081 (2013-01-15)
We compared the binding affinities of ground state analogues for bacterial ketosteroid isomerase (KSI) with a wild-type anionic Asp general base and with uncharged Asn and Ala in the general base position to provide a measure of potential ground state
Vasant Muralidharan et al.
Nature communications, 3, 1310-1310 (2012-12-20)
One-fourth of Plasmodium falciparum proteins have asparagine repeats that increase the propensity for aggregation, especially at elevated temperatures that occur routinely in malaria-infected patients. Here we report that a Plasmodium Asn repeat-containing protein (PFI1155w) formed aggregates in mammalian cells at
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