11134
Ascomycin
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About This Item
Empirical Formula (Hill Notation):
C43H69NO12
CAS Number:
Molecular Weight:
792.01
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
5372600
SMILES string
CCC1\C=C(C)\C[C@H](C)C[C@H](OC)C2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)OC([C@H](C)[C@@H](O)CC1=O)\C(C)=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
storage temp.
−20°C
General description
Chemical structure: macrolactam
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Jost Klawitter et al.
Chemical research in toxicology, 22(1), 118-128 (2008-12-23)
The clinical use of the immunosuppressant calcineurin inhibitor cyclosporine is limited by its nephrotoxicity. This is enhanced when combined with the immunosuppressive mTOR inhibitor sirolimus. Nephrotoxicity of both drugs is not yet fully understood. The goal was to gain more
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