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Key Documents

Safety Information

11134

Sigma-Aldrich

Ascomycin

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About This Item

Empirical Formula (Hill Notation):
C43H69NO12
CAS Number:
Molecular Weight:
792.01
Beilstein:
5372600
MDL number:
UNSPSC Code:
12352200

antibiotic activity spectrum

fungi

Mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

CCC1\C=C(C)\C[C@H](C)C[C@H](OC)C2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)OC([C@H](C)[C@@H](O)CC1=O)\C(C)=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC

General description

Chemical structure: macrolactam

replaced by

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Jost Klawitter et al.
Chemical research in toxicology, 22(1), 118-128 (2008-12-23)
The clinical use of the immunosuppressant calcineurin inhibitor cyclosporine is limited by its nephrotoxicity. This is enhanced when combined with the immunosuppressive mTOR inhibitor sirolimus. Nephrotoxicity of both drugs is not yet fully understood. The goal was to gain more

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