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104094

Sigma-Aldrich

Piperidine

ReagentPlus®, 99%

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Synonym(s):
Hexahydropyridine
Empirical Formula (Hill Notation):
C5H11N
CAS Number:
110-89-4
Molecular Weight:
85.15
Beilstein:
102438
EC Number:
203-813-0
MDL number:
MFCD00005979
UNSPSC Code:
12352100
PubChem Substance ID:
24846636
NACRES:
NA.21

vapor density

2.94 (vs air)
3 (vs air)

Quality Level

200

vapor pressure

23 mmHg ( 20 °C)
23 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

99%

impurities

≤0.5% water (Karl Fischer)

refractive index

n20/D 1.452 (lit.)

bp

106 °C (lit.)

mp

−13 °C (lit.)

solubility

organic solvents: soluble(lit.)
water: miscible(lit.)

density

0.862 g/mL at 20 °C (lit.)

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChI key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

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General description

Piperidine can be prepared either by nickel catalyzed hydrogenation of pyridine or by cobalt catalyzed hydrogenolysis of tetrahydrofurylamine It forms adducts with α,β,γ,δ-tetraphenylporphyriniron(II) and protoporphyriniron(II). Mossbauer spectra of these adducts have been evaluated. It constitutes the skeleton of various alkaloids. Its chemical reactivity has been discussed.

Application

Piperidine may be employed as protective and structure-directing agent in the post synthesis of MCM (Mobil Composition of Matter)-49 zeolites.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rubiralta M, et al.
Piperidine: Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and its Derivatives, 43, 2-2 (2013)
Alma Andersson et al.
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In the past decades, transcriptomic studies have revolutionized cancer treatment and diagnosis. However, tumor sequencing strategies typically result in loss of spatial information, critical to understand cell interactions and their functional relevance. To address this, we investigate spatial gene expression
Moessbauer spectra of some porphyrin complexes with pyridine, piperidine, and imidazole.
Epstein LM, et al.
Inorganic Chemistry, 6(9), 1720-1724 (1967)
Roberto Alcántara et al.
STAR protocols, 2(4), 100878-100878 (2021-10-05)
Here, we describe a detailed step-by-step protocol to detect SARS-CoV-2 RNA using RT-PCR-mediated amplification and CRISPR/Cas-based visualization. The optimized assay uses basic molecular biology equipment such as conventional thermocyclers and transilluminators for qualitative detection. Alternatively, a fluorescence plate reader can
Stephanie Beltz et al.
Bio-protocol, 7(2), e2112-e2112 (2017-01-20)
The direct regulation of a mycobacterial adenylate cyclase (Rv1625c) via exchange of its membrane anchor by the quorum sensing receptor CqsS (Vibrio harveyi) has recently been reported ( Beltz et al., 2016 ). This protocol describes the expression and membrane
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