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Merck
CN

10039

Amoxicillin

≥97.0% (dried material, NT)

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S
CAS Number:
26787-78-0
Molecular Weight:
365.40
EC Number:
248-003-8
UNSPSC Code:
51101500
MDL number:
MFCD00056860
Beilstein/REAXYS Number:
7507120

Key Documents

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InChI

1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1

InChI key

LSQZJLSUYDQPKJ-NJBDSQKTSA-N

SMILES string

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

assay

≥97.0% (dried material, NT)

impurities

~15% water

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

General description

Chemical structure: β-lactam

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

涉药品监管产品
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László Szabó et al.
Free radical research, 50(1), 26-38 (2015-10-03)
Penicillins, as bactericidal antibiotics, have been widely used to treat infections for several decades. Their structure contains both aromatic and thioether moieties susceptible to free radical oxidation. The (•)OH induced oxidation mechanism of amoxicillin was investigated by pulse radiolysis techniques
Thao Thi Nguyen et al.
Scientific reports, 9(1), 9349-9349 (2019-06-30)
This study investigates the photocatalytic degradation of amoxicillin (AMO) by simulated solar irradiation using WO3 as a catalyst. A three-factor-three-level Box-Behnken design (BBD) consisting of 30 experimental runs is employed with three independent variables: initial AMO concentration, catalyst dosage, and
Allison R Bechard et al.
Behavioral neuroscience, 133(2), 247-254 (2019-02-05)
Research using the cocaine self-administration and reinstatement animal model of relapse finds that the beta-lactam antibiotic, ceftriaxone, attenuates cocaine-primed reinstatement of cocaine seeking and upregulates two proteins that regulate glutamate release and reuptake (xCT and GLT-1, respectively) in the nucleus
Jakob Menz et al.
Environmental science & technology, 52(11), 6555-6564 (2018-04-10)
There are growing concerns that antibiotic pollution impacts environmental microbiota and facilitates the propagation of antibiotic resistance. However, the prediction or analytical determination of bioavailable concentrations of antibiotics in soil is still subject to great uncertainty. Biological assays are increasingly

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