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Merck
CN

09170

4-Aminophenol hydrochloride

≥99.0% (AT)

Synonym(s):

4-Hydroxyaniline hydrochloride

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About This Item

Linear Formula:
H2NC6H4OH · HCl
CAS Number:
51-78-5
Molecular Weight:
145.59
UNSPSC Code:
12352107
NACRES:
NA.25
PubChem Substance ID:
329748716
EC Number:
200-122-6
Beilstein/REAXYS Number:
3911747
MDL number:
MFCD00012996

Key Documents

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Quality Level

200

InChI key

RVGOBWDGAVAVPJ-UHFFFAOYSA-N

InChI

1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H

SMILES string

Cl[H].Nc1ccc(O)cc1

assay

≥99.0% (AT)

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Application

4-Aminophenol hydrochloride can be used to study cell biology, bioactive small molecules, chemical synthesis, organic building blocks, oxygen compounds and phenols. 4-Aminophenol hydrochloride has been used to study ferrihemoglobin and kidney lesions in rats.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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M Kiese et al.
Archives of toxicology, 34(4), 337-340 (1975-12-18)
4-Dimethylaminophenol hydrochloride (DMAP), 20mg/kg i.v., was found to oxidize in rats as much as 50% of the hemoglobin to ferrihemoglobin but did not cause kidney lesions. 4-Aminophenol hydrochloride, 400 mg/kg i.v., oxidized only 25% of the hemoglobin and produced large
Mohammad Mahdi Najafpour et al.
Dalton transactions (Cambridge, England : 2003), 41(14), 3906-3910 (2012-02-14)
We describe here the ability of manganese oxide monosheets to aggregate to form layered structures with 4-aminophenol molecules. These aggregated monosheets could be considered as the first step to synthesize a self-assembled layered hybrid of phenol-manganese ions with phenol and
Yanpeng Xue et al.
Journal of colloid and interface science, 379(1), 89-93 (2012-05-23)
In this study, a facile one-step redox polymerization method for the preparation of highly dispersed palladium (Pd)/polypyrrole (PPy) nanocapsules has been demonstrated. During the polymerizaion process, the formation of RB-PdCl(4)(2-) complex via an electrostatic interaction plays a key role for
Annette John-Baptiste et al.
International journal of toxicology, 31(6), 529-536 (2012-11-03)
Kidney injury biomarkers have been utilized by pharmaceutical companies as a means to assess the potential of candidate drugs to induce nephrotoxicity. Multiple platforms and assay methods exist, but the comparison of these methods has not been described. Millipore's Kidney
Tomoyuki Yasukawa et al.
Biosensors & bioelectronics, 37(1), 19-23 (2012-05-23)
In this work, a novel immunosensing method has been developed on the basis of the sensitive determination of a product generated by an enzyme reaction with dual amplification system combining an electrochemical-redox cycling and coulometric signal transduction using a galvanic
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