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08982

Supelco

Sodium metabisulfite

analytical standard

Synonym(s):

E223, Sodium disulfite, Sodium pyrosulfite

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About This Item

Linear Formula:
Na2S2O5
CAS Number:
Molecular Weight:
190.11
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
E Number:
E223
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (iodometric, RT)

shelf life

limited shelf life, expiry date on the label

mp

>300 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
thiosulfate (S2O32-): ≤500 mg/kg

cation traces

As: ≤0.5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

[Na+].[Na+].[O-]S(=O)S([O-])(=O)=O

InChI

1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

InChI key

HRZFUMHJMZEROT-UHFFFAOYSA-L

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General description

Sodium metabisulfite is primarily used as an antioxidant and antimicrobial agent in a wide variety of foods and drugs. It is also used as the main additive in the prevention of melanosis in shrimp.

Application

Sodium metabisulfite may be used as an antioxidant which when added to anesthetic formulations serves to minimize epinephrine oxidation in the quantification of epinephrine in dental anesthetic solutions by capillary electrophoresis. Sodium metabisulfite may also be used as a standard in the determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection.

Analysis Note

metal trace analysis: corresponds to requirements

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Supplementary Hazards

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection.
Raggi MA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 730(2), 201-211 (1999)
The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts.
Zhang Q, et al.
Regulatory Toxicology and Pharmacology, 72(3), 440-446 (2015)
Quantitative assay for epinephrine in dental anesthetic solutions by capillary electrophoresis.
Kranack A and Chen DY
Analyst, 123(7), 1461-1463 (1998)
Standardization of sodium metabisulfite solution concentrations and immersion time for farmed shrimp Litopenaeus vannamei.
Andrade LTD, et al.
Ciencia Rural, 45(3), 499-504 (2015)
Ivana Mara da Costa Machado Matos Carvalho et al.
Chemosphere, 82(7), 1056-1061 (2010-11-09)
Sodium metabisulfite is used in marine shrimp harvesting to prevent the occurrence of black spots. Shrimps are soaked in a sodium metabisulfite solution in ice, which is disposed of in sewages that run into marine canals, creating an environmental hazard.

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