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Merck
CN

07767

N,N-Dimethyl-p-phenylenediamine dihydrochloride

≥99.5% (HPLC)

Synonym(s):

4-Amino-N,N-dimethylaniline dihydrochloride, DMPD · 2HCl, DMPPDA · 2HCl

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About This Item

Linear Formula:
(CH3)2NC6H4NH2 · 2HCl
CAS Number:
536-46-9
Molecular Weight:
209.12
EC Number:
208-635-7
UNSPSC Code:
12171500
PubChem Substance ID:
329748516
Beilstein/REAXYS Number:
3913463
MDL number:
MFCD00012991

Key Documents

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InChI key

IAEDWDXMFDKWFU-UHFFFAOYSA-N

InChI

1S/C8H12N2.2ClH/c1-10(2)8-5-3-7(9)4-6-8;;/h3-6H,9H2,1-2H3;2*1H

SMILES string

Cl[H].Cl[H].CN(C)c1ccc(N)cc1

assay

≥99.5% (HPLC)

mp

222 °C (dec.) (lit.)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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Other Notes

Quantitation of labile sulfide in proteins by the "methylene blue" method; Detection of sterol hydroperoxides on irrigated thin-layer chromato-plates using N,N-dimethyl-p-phenylenediamine dihydrochloride; Preparation of the "nadi reagent" and demonstration of cytochrome oxidase activity in chick embryos

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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F. Moog
Journal of Cellular and Comparative Physiology, 22, 223-223 (1943)
Analysis of acid-labile sulfide and sulfhydryl groups.
J C Rabinowitz
Methods in enzymology, 53, 275-277 (1978-01-01)
Detection of sterol hydroperoxides on thin-layer chromatoplates by means of the Wurster dyes.
L L Smith et al.
Journal of chromatography, 66(1), 101-109 (1972-03-22)
S Marroquí et al.
Journal of bacteriology, 183(3), 854-864 (2001-02-24)
We isolated a Tn5-induced Rhizobium tropici mutant that has enhanced capacity to oxidize N,N-dimethyl-p-phenylendiamine (DMPD) and therefore has enhanced respiration via cytochrome oxidase. The mutant had increased levels of the cytochromes c(1) and CycM and a small increase in the
Veronica Verde et al.
Free radical research, 36(8), 869-873 (2002-11-08)
Oxidative stress has been clearly implicated in human disease by a growing body of scientific evidences. There is no ideal method for the measurement of this parameter. A possible strategy would be to measure simultaneously several biomarkers representing damage to
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