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Merck
CN

07618

trans-2-Aminocyclohexanecarboxylic acid

≥97.0%

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About This Item

Empirical Formula (Hill Notation):
C7H13NO2
CAS Number:
Molecular Weight:
143.18
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3196018
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InChI

1S/C7H13NO2/c8-6-4-2-1-3-5(6)7(9)10/h5-6H,1-4,8H2,(H,9,10)/t5-,6-/m1/s1

SMILES string

N[C@@H]1CCCC[C@H]1C(O)=O

InChI key

USQHEVWOPJDAAX-PHDIDXHHSA-N

assay

≥97.0%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

white to faint beige

mp

~255 °C (dec.)

application(s)

peptide synthesis

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Anasztázia Hetényi et al.
Journal of the American Chemical Society, 127(2), 547-553 (2005-01-13)
Homo-oligomers constructed by using trans-2-aminocyclohexanecarboxylic acid monomers without protecting groups were studied. Both ab initio theory and NMR measurements showed that the tetramer tends to adopt a 10-helix motif, while the pentamer and hexamer form the known 14-helix. It was
Betas are brought into the fold.
B L Iverson
Nature, 385(6612), 113-113 (1997-01-09)
William C Pomerantz et al.
Journal of the American Chemical Society, 133(34), 13604-13613 (2011-08-06)
We have examined the effect of β-peptide modifications on the propensity of these helical molecules to form lyotropic liquid crystalline (LC) phases in water. All of the β-peptides we have examined contain 10 residues. In each case, at least three
D H Appella et al.
Nature, 387(6631), 381-384 (1997-05-22)
Proteins and RNA are unique among known polymers in their ability to adopt compact and well-defined folding patterns. These two biopolymers can perform complex chemical operations such as catalysis and highly selective recognition, and these functions are linked to folding
Nóra V Nagy et al.
Inorganic chemistry, 51(3), 1386-1399 (2012-01-10)
With the aim of an improved understanding of the metal-complexation properties of alicyclic β-amino acid stereoisomers, and their peptides, the complex equilibria and modes of coordination with copper(II) of L-phenylalanine (F) derivatives of cis/trans-2-aminocyclohexanecarboxylic acid (c/tACHC), i.e. the dipeptides F-c/tACHC

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