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Safety Information

07604

SAFC

2-Mercaptoethanol

Pharma Manufacturing

Synonym(s):

2-Mercaptoethanol, β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylene glycol

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About This Item

Linear Formula:
HSCH2CH2OH
CAS Number:
60-24-2
Molecular Weight:
78.13
Beilstein:
773648
EC Number:
200-464-6
MDL number:
MFCD00004890
UNSPSC Code:
12161504
NACRES:
NA.21

biological source

synthetic

Quality Level

400

vapor density

2.69 (vs air)

vapor pressure

1 mmHg ( 20 °C)

Assay

≥99.0% (GC)
99.0-101.0% (iodometric, RT)

form

liquid

expl. lim.

18 %

concentration

14.3 M (pure liquid)

refractive index

n20/D 1.500 (lit.)

bp

157 °C (lit.)

solubility

H2O: 1 mL/mL, clear, colorless

density

1.114 g/mL at 25 °C (lit.)

cation traces

Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
Ni: ≤1 mg/kg
Pb: ≤5 mg/kg
Zn: ≤1 mg/kg

storage temp.

2-8°C

SMILES string

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

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Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

Target Organs

Liver,Heart

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

165.2 °F - closed cup

Flash Point(C)

74 °C - closed cup

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF5677
BCBP7089V
BCBP7091V
BCBP7090V

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