Skip to Content
Merck
CN
All Photos(1)

Key Documents

Safety Information

06594

Sigma-Aldrich

(S)-α-Allyl-proline hydrochloride

purum, ≥98.0% (TLC)

Synonym(s):

α-Allyl-D-proline hydrochloride, (S)-2-Allyl-2-pyrrolidinecarboxylic acid hydrochloride

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C8H13NO2 · HCl
CAS Number:
Molecular Weight:
191.66
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

grade

purum

Quality Level

Assay

≥98.0% (TLC)

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

off-white to brown

mp

186-190 °C

application(s)

peptide synthesis

SMILES string

Cl.OC(=O)[C@]1(CCCN1)CC=C

InChI

1S/C8H13NO2.ClH/c1-2-4-8(7(10)11)5-3-6-9-8;/h2,9H,1,3-6H2,(H,10,11);1H/t8-;/m1./s1

InChI key

DIYYEOOBZVTROL-DDWIOCJRSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Emily M Christensen et al.
The Journal of biological chemistry, 295(52), 18316-18327 (2020-10-29)
Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Δ1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H. Many cancers alter their proline metabolism by up-regulating the proline cycle and proline biosynthesis, and knockdowns of

Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service