06369
Lipid binding constant determination kit
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352200
contains
0.0005% NaN3 as preservative
concentration
30-35 mM lipid (Transil®-L pellet)
surface area
~10 m2/g
particle size
~30 μm
pore size
~4000 Å pore diameter
storage temp.
2-8°C
Application
Lipid binding constant determination kit is used for analysis of lipid binding.
Other Notes
TRANSIL®-Ln (neutral biomembrane);
1 mL TRANSIL®-Lc (biomembrane with negative charge clusters); 1 ml
each in 5 mL buffer (20 mM HEPES pH 7.0; 0.03 M NaCl)
TRANSIL®-L consists of a silicate core; encased in a mobile lipid bilayer (phospholipids).
1 mL TRANSIL®-Lc (biomembrane with negative charge clusters); 1 ml
each in 5 mL buffer (20 mM HEPES pH 7.0; 0.03 M NaCl)
TRANSIL®-L consists of a silicate core; encased in a mobile lipid bilayer (phospholipids).
Legal Information
Transil is a registered trademark of Nimbus GmbH
Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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A Loidl-Stahlhofen et al.
Pharmaceutical research, 18(12), 1782-1788 (2002-01-12)
Lipid-water partitioning of 187 pharmaceuticals has been assessed with solid-supported lipid membranes (TRANSIL) in microwell plates and with multilamellar liposomes for a data comparison. The high-throughput potential of the new approach was evaluated. Drugs were incubated at pH 7.4 with
A Loidl-Stahlhofen et al.
Journal of pharmaceutical sciences, 90(5), 599-606 (2001-04-05)
Quantification of membrane affinity is an important early screening step in modern drug design. However, current approaches using different lipid membrane models usually are time-consuming or show severe experimental drawbacks. In this paper we describe the use of solid-supported lipid
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