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Mangiferin

analytical standard

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Synonym(s):
1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, Chinomin, Chinonin, Shamimin
Empirical Formula (Hill Notation):
C19H18O11
CAS Number:
Molecular Weight:
422.34
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

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General description

Mangiferin is a xanthone glucoside and a naturally occurring polyphenol found abundantly in the plants of genus Mangifera particularly Mangifera indica L. and also in some medicinal herbs. Mangiferin exhibits antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects and is considered to be of high research interest due to its therapeutic properties.

Application

Mangiferin may be used as an analytical standard for the determination of the analyte in rat plasma, traditional Chinese medicines and honeybush tea (Cyclopia spp.) by chromatography based techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine
Geodakyan SV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 577(2), 371-375 (1992)
Dandan Han et al.
Journal of pharmaceutical and biomedical analysis, 51(1), 260-263 (2009-08-25)
An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method employing electrospray ionization (ESI) has been developed for the determination of mangiferin in rat plasma using diphenhydramine as the internal standard (IS). Liquid-liquid extraction (LLE) was used for sample preparation and
Ronghua Dai et al.
Journal of chromatographic science, 42(4), 207-210 (2004-05-25)
High-performance liquid chromatography is employed to determine the contents of six marker components such as mangiferin, jateorrhizine, palmatine, berberine, cinnamic acid, and cinnamaldehyde in the traditional Chinese medicinal preparation Zi-Shen pill. The separation is performed on a C(18) column by
Reversed-phase HPLC determination of mangiferin, isomangiferin and hesperidin in Cyclopia and the effect of harvesting date on the phenolic composition of C. genistoides
Joubert E, et al.
European Food Research and Technology, 216(3), 270-273 (2003)
Dominika Zajac et al.
Advances in experimental medicine and biology, 756, 105-111 (2012-07-28)
Mangiferin, the main active substance of the mango tree bark (Mangifera indica L.), is known for its use in natural medicine, not only as a health enhancing panacea or adjunct therapeutic, but also for brain functions improvement. In this context

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