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05506

Supelco

(15:0)-Anacardic acid

analytical standard

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Synonym(s):
Anacardic acid, 2-Hydroxy-6-pentadecylbenzoic acid, 22:0-Anacardic acid, 6-Pentadecylsalicylic acid
Empirical Formula (Hill Notation):
C22H36O3
CAS Number:
Molecular Weight:
348.52
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O

InChI

1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)

InChI key

ADFWQBGTDJIESE-UHFFFAOYSA-N

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General description

(15:0)-Anacardic acid is a mixture of salicylic acid analogues, comprising of a 15 carbon aliphatic side chain in various degrees of unsaturation.

Biochem/physiol Actions

Anacardic acid is a HAT (Histone Acetyltransferase) inhibitor.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Uncoupling effect of anacardic acids from cashew nut shell oil on oxidative phosphorylation of rat liver mitochondria.
Toyomizu M, et al.
Life Sciences, 66(3), 229-234 (1999)
Rikke Illum Høgh et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(11), 15531-15546 (2020-10-01)
SCFAs are primarily produced in the colon by bacterial fermentation of nondigestible carbohydrates. Besides providing energy, SCFAs can suppress development of colon cancer. The mechanism, however, remains elusive. Here, we demonstrate that the SCFA propionate upregulates surface expression of the
E Pieterse et al.
Clinical and experimental immunology, 179(1), 68-74 (2014-04-25)
In addition to disturbed apoptosis and insufficient clearance of apoptotic cells, there is recent evidence for a role of neutrophils in the aetiopathogenesis of systemic lupus erythematosus (SLE). In response to various stimuli, neutrophils can rapidly release DNA fibres decorated
Mi Ae Kang et al.
International journal of oncology, 46(1), 342-350 (2014-10-24)
The tumor suppressor p53 plays a key role in regulation of the cell cycle, apoptosis and senescence in response to various stresses. We screened a library of 7920 chemical compounds for the p53 activator and identified N-[2-(dimethylamino)ethyl]-2,3-dimethyl-4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-9-carboxamide (PTP), which significantly
Tomohisa Horibe et al.
Chembiochem : a European journal of chemical biology, 15(11), 1599-1606 (2014-06-13)
In order to regulate the activity of P5, which is a member of the protein disulfide isomerase family, we screened a chemical compound library for P5-specific inhibitors, and identified two candidate compounds (anacardic acid and NSC74859). Interestingly, anacardic acid inhibited

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