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04885

Supelco

L-Ascorbic acid 6-stearate

analytical standard

Synonym(s):

6-O-Stearyl-L-ascorbic acid, L-Ascorbyl 6-octadecanoate, Ascorbyl stearate

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About This Item

Empirical Formula (Hill Notation):
C24H42O7
CAS Number:
10605-09-1
Molecular Weight:
442.59
EC Number:
234-231-5
UNSPSC Code:
12352200
PubChem Substance ID:
329747987
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

format

neat

InChI

1S/C24H42O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(26)30-18-19(25)23-21(27)22(28)24(29)31-23/h19,23,25,28-29H,2-18H2,1H3

InChI key

NRHBEGWPKVFGRH-UHFFFAOYSA-N

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General description

L-Ascorbic acid 6-stearate is a lipophilic fatty acid ester of ascorbic acid.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Application

L-Ascorbic acid 6-stearate (ASC-S) may be used as a standard in determining the apoptotic activity of ASC-S through the intrinsic mitochondrial pathway in HeLa cell lines, derived from cervical cancer cells. It may also be used as an analytical standard to investigate its interaction with bovine serum albumin using surface plasmon resonance (SPR).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB5544
BCBX0830
BCBT7040
BCBS0118V
BCBS0118

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P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells
Naidu AK, et al.
Anticancer Research, 27(6B), 3927-3934 (2007)
Ascorbyl stearate promotes apoptosis through intrinsic mitochondrial pathway in HeLa cancer cells
Mane DS, et al.
Anticancer Research, 36(12), 6409-6417 (2016)
Kinetic and thermodynamic studies of bovine serum albumin interaction with ascorbyl palmitate and ascorbyl stearate food additives using surface plasmon resonance
Fathi F, et al.
Food Chemistry, 246(6B), 228-232 (2018)

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