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Eukitt® Quick-hardening mounting medium

for microscopy

Synonym(s):

Poly(butyl methacrylate-co-methyl methacrylate)

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About This Item

Linear Formula:
[CH2C(CH3)[CO2(CH2)3CH3]]X[CH2C(CH3)(CO2CH3)]Y
CAS Number:
25608-33-7
MDL number:
MFCD00145620
UNSPSC Code:
41116121
PubChem Substance ID:
24845633
NACRES:
MA.02

grade

for microscopy

Quality Level

100

form

liquid

color

yellow

refractive index

n/D 1.490-1.500

viscosity

250-500 mPa.s, neat(25 °C)(lit.)

solubility

water: insoluble

suitability

in accordance for application

application(s)

hematology
histology

storage temp.

room temp

SMILES string

COC(=O)C(C)=C.CCCCOC(=O)C(C)=C

InChI

1S/C8H14O2.C5H8O2/c1-4-5-6-10-8(9)7(2)3;1-4(2)5(6)7-3/h2,4-6H2,1,3H3;1H2,2-3H3

InChI key

WHLPIOPUASGRQN-UHFFFAOYSA-N

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General description

Eukitt® Quick-hardening mounting medium, or Poly(butyl methacrylate-co-methyl methacrylate), is a mounting medium for microscopy, containing 45% acrylic resin and 55% xylenes. It is a special-purpose adhesive, sealant, and specimen preservative that can be used manually and in automated cover-slipping equipment, glass, non-plastic, and other non-reactive materials.

Application

  • It has been used in histomorphometry to study the use of gambogic amide for augmenting skeletal adaptation to mechanical forces without inducing hyperalgesia.
  • It has been used in immunohistochemistry and immunofluorescence to document the global location of coxsackievirus and adenovirus receptors in the mouse brain.
  • It has been used in immunocytochemistry to study the function of matrix metalloproteinases in regulating cancer invasiveness.

Features and Benefits

  • Spreads quickly and evenly without forming any air bubbles.
  • Non-yellowing, unaffected by cold, and stays optically clear for over 10 years.

Physical properties

Fast-drying (20 minutes), Refractive index close to that of glass (1.510), chemically neutral, little sensitivity to water, no reaction to staining, temperature limits: 42°C-17°C, not affected by ultraviolet light, non yellowing, unaffected by cold, stays optically clear for over 10 years, can be used in place of epoxy resins for mounting petrographic thin sections, used in fluorescence dyes in bones.

Legal Information

Eukitt is a registered trademark of Orsatec GmbH

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Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system,Liver,Kidney, Respiratory system

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Gabriella Fioravanti et al.
Bone, 147, 115908-115908 (2021-03-14)
The periosteal and endosteal surfaces of mature bone are densely innervated by sensory nerves expressing TrkA, the high-affinity receptor for nerve growth factor (NGF). In previous work, we demonstrated that administration of exogenous NGF significantly increased load-induced bone formation through
The TrkA agonist gambogic amide augments skeletal adaptation to mechanical loading
Fioravanti, et al.
Bone (2021)
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Oncology reports, 37(5), 3055-3060 (2017-04-26)
Triple-negative breast cancer is a highly aggressive type of mammalian carcinoma. It is defined by a rather weak expression of estrogen-, progesterone- and Her2-receptor, and is thus difficult to treat, resulting in low disease-free and overall survival rates of the
E A Armstrong et al.
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In commercial flocks of laying hens, keel bone fractures (KBFs) are prevalent and associated with behavioural indicators of pain. However, whether their impact is severe enough to induce a depressive-like state of chronic stress is unknown. As chronic stress downregulates
Baihui Li et al.
Journal of autoimmunity, 90, 132-145 (2018-03-01)
Sjögren's syndrome is a multifactorial systemic autoimmune disorder characterized by lymphocytic infiltrates in exocrine organs. Patients present with sicca symptoms, such as extensive dry eyes and dry mouth, and parotid enlargement. Other serious complications include profound fatigue, chronic pain, major
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