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03854

Sigma-Aldrich

Creosote from beechwood tar

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Synonym(s):
Beechwood creosote
CAS Number:
8021-39-4
MDL number:
MFCD00146582
UNSPSC Code:
12352401
NACRES:
NA.25

Quality Level

100

ign. residue

≤0.01% (as SO4)

bp

200-220 °C (lit.)

transition temp

solidification point <−20 °C

density

1.09 g/mL at 20 °C

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

InChI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChI key

LHGVFZTZFXWLCP-UHFFFAOYSA-N

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General description

Beechwood creosote is a colorless to yellowish greasy liquid obtained from the distillation of wood tar. It comprises of phenol, 4-methylphenol, 2-methoxyphenol, and 2-methoxy-4-methylphenol as its major volatile constituents.

Application

Creosote from beechwood tar has been used as raw material in the synthesis of phenolic branched-chain fatty acids (n-PBC-FA) in the presence of a modified H+ Ferrierite zeolite catalyst.

Biochem/physiol Actions

Creosote from beechwood tar has been reported to exhibit antioxidant activity comparable to that of popular antioxidants α-tocopherol and butylated hydroxytoluene (BHT). It is used as a herbal antidiarrheal medicine owing to its antisecretory activity. Beechwood creosote has also been found to show bactericidal, fungicidal and laxative action.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1A - STOT RE 2

Target Organs

Nervous system,Kidney,Liver,Skin

WGK

WGK 3

Flash Point(F)

165.2 °F

Flash Point(C)

74 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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Bio-based phenolic-branched-chain fatty acid isomers synthesized from vegetable oils and natural monophenols using modified H+-Ferrierite zeolite
Yan Z, et al.,
Industrial Crops and Products, 114 (2018)
Korean Beechwood Creosote as a Substitute to an Antibiotic for Post Weaning Diarrhea in Piglets.
Sodhi S, et al.,
Pakistan Veterinary Journal, 34(3) (2014)
Dawoon Jung et al.
Aquatic toxicology (Amsterdam, Netherlands), 95(1), 44-51 (2009-09-04)
Benzo[a]pyrene (BaP) is a known genotoxicant that affects both mitochondrial and nuclear DNA (mtDNA, nDNA). Here, we examined mtDNA and nDNA damage in the Atlantic killifish (Fundulus heteroclitus) from a highly contaminated Superfund site (Elizabeth River, VA, USA) and from
Göran Bengtsson et al.
Microbial ecology, 65(1), 91-100 (2012-09-04)
We analyzed the within-site spatial heterogeneity of microbial community diversity, polyaromatic hydrocarbon (PAH) catabolic genotypes, and physiochemical soil properties at a creosote contaminated site. Genetic diversity and community structure were evaluated from an analysis of denaturant gradient gel electrophoresis (DGGE)
Nobuaki Moriguchi et al.
Yakushigaku zasshi, 46(1), 13-20 (2011-12-15)
Wood creosote is a medicine that has been listed in the Japanese Pharmacopoeia (JP) since the first edition published in 1886. Medicines containing wood creosote and other natural ingredients have been very popular in Japan and Southeast Asian countries. In
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