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Ethylene glycol salicylate, Salicylic acid 2-hydroxyethyl ester, Salicylic acid ethylene glycol ester
HOC6H4COOCH2CH2OH
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Quality Level
Assay
≥98.0% (GC)
form
liquid
refractive index
n20/D 1.548 (lit.)
n20/D 1.549
bp
166 °C/13 mmHg (lit.)
density
1.244 g/mL at 25 °C (lit.)
SMILES string
OCCOC(=O)c1ccccc1O
InChI
1S/C9H10O4/c10-5-6-13-9(12)7-3-1-2-4-8(7)11/h1-4,10-11H,5-6H2
InChI key
LVYLCBNXHHHPSB-UHFFFAOYSA-N
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Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
339.8 °F
Flash Point(C)
171 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate.
Contact dermatitis, 47(2), 120-121 (2002-11-29)
Contact dermatitis from hydroxyethyl salicylate.
Contact dermatitis, 33(4), 275-276 (1995-10-01)
Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate.
Dermatitis : contact, atopic, occupational, drug, 22(3), 171-172 (2011-05-17)
Arzneimittel-Forschung, 53(12), 850-856 (2004-01-22)
A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy and
British journal of clinical pharmacology, 46(1), 29-35 (1998-08-05)
The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controversy as to whether these agents are capable of direct penetration by diffusion through
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