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Merck
CN

03761

Fumaric acid

≥99.5%, fine crystals, tested according to USP/NF

Synonym(s):

(2E)-2-Butenedioic acid, trans-Butenedioic acid, Acidum fumaricum

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About This Item

Linear Formula:
HOOCCH=CHCOOH
CAS Number:
Molecular Weight:
116.07
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39021709
UNSPSC Code:
12352100
EC Number:
203-743-0
MDL number:
Beilstein/REAXYS Number:
605763
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Product Name

Fumaric acid, tested according to USP/NF

InChI key

VZCYOOQTPOCHFL-OWOJBTEDSA-N

InChI

1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+

SMILES string

OC(=O)\C=C\C(O)=O

agency

tested according to USP/NF

vapor pressure

1.7 mmHg ( 165 °C)

assay

≥99.5%

form

fine crystals
powder

autoignition temp.

1364 °F

expl. lim.

40 %

mp

298-300 °C (subl.) (lit.)

application(s)

pharmaceutical (small molecule)

functional group

carboxylic acid

Quality Level

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Application

Fumaric acid may be used in the preparation of L-Lysine-fumaric acid crystals.

General description

Fumaric acid or trans-butenedioic acid, is crystalline compound that occurs widely in nature.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

523.4 °F

flash_point_c

273 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves


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UV-curable methacrylated/fumaric acid modified epoxy as a potential support for enzyme immobilization.
Kahraman MV, et al.
Reactive functional Polymers, 67(2), 97-103 (2007)
C J Newbold et al.
The British journal of nutrition, 94(1), 27-35 (2005-08-24)
Fifteen potential precursors of propionate were tested for their ability to decrease CH4 production by ruminal fluid in vitro. Sodium acrylate and sodium fumarate produced the most consistent effects in batch cultures, with 50 % of the added precursors being
Comparison of dilute mineral and organic acid pretreatment for enzymatic hydrolysis of wheat straw.
Kootstra AMJ, et al.
Biochemical Engineering Journal, 46(2), 126-131 (2009)
N Cao et al.
Applied and environmental microbiology, 62(8), 2926-2931 (1996-08-01)
An integrated system of simultaneous fermentation-adsorption for the production and recovery of fumaric acid from glucose by Rhizopus oryzae was investigated. The system was constructed such that growing Rhizopus mycelia were self-immobilized on the plastic discs of a rotary biofilm
Vibrational spectra and second harmonic generation in molecular complexes of L-lysine with L-tartaric, D, L-malic, acetic, arsenous, and fumaric acids.
Marchewka MK, et al.
Crystal Growth & Design, 3(4), 587-592 (2003)

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