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Safety Information

02390

Sigma-Aldrich

1,2-Ethanedithiol

≥98.0% (GC)

Synonym(s):

1,2-Dimercaptoethane, Dithioglycol, Ethylene mercaptan

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5 μG
¥4,526.72
20 μG
¥11,100.17

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5 μG
¥4,526.72
20 μG
¥11,100.17

About This Item

Linear Formula:
HSCH2CH2SH
CAS Number:
540-63-6
Molecular Weight:
94.20
Beilstein:
505946
EC Number:
208-752-3
MDL number:
MFCD00004892
UNSPSC Code:
12352100
PubChem Substance ID:
329747425
NACRES:
NA.22

¥4,526.72

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vapor density

>1 (vs air)

Quality Level

200

vapor pressure

4.8 mmHg ( 20 °C)

Assay

≥98.0% (GC)

form

liquid

refractive index

n20/D 1.558 (lit.)
n20/D 1.558

bp

144-146 °C (lit.)

mp

−41 °C (lit.)

density

1.123 g/mL at 25 °C (lit.)

functional group

thiol

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1 of 4

This Item
P1787P8538P0194
Protein kinase Cα isozyme human ≥70% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution

P1782

Protein kinase Cα isozyme human

Protein Kinase CβI isozyme human ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution

P1787

Protein Kinase CβI isozyme human

Protein Kinase Cδ isozyme human >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution

P8538

Protein Kinase Cδ isozyme human

Protein Kinase Cζ isozyme human ≥75% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution

P0194

Protein Kinase Cζ isozyme human

Gene Information

human ... PRKCA(5578)

Gene Information

human ... PRKCB(5579)

Gene Information

human ... PRKCD(5580)

Gene Information

human ... PRKCZ(5590)

assay

≥70% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

≥75% (SDS-PAGE)

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected insect cells

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous solution

UniProt accession no.

P17252

UniProt accession no.

P05771

UniProt accession no.

Q05655

UniProt accession no.

Q05513

General description

1,2-Ethanedithiol (EDT) is an organosulfur compound that is used as an organic building block in chemical synthesis. It is also used as a ligand for metal ions to prepare metal complexes.

Application

1,2-Ethanedithiol can be used to synthesize:      
  • 1,3-Dithiolanes by reacting with aldehydes or ketones.
  • Dithiazepan-3-yl-alkanoic acids by cyclocondensation reaction with amino acids and formaldehyde.
  • EDT can also be used as a scavenger in solid phase peptide synthesis for the efficient deprotection of the peptide resin.

Pictograms

FlameSkull and crossbones
GHS02,GHS06

Signal Word

Danger

Hazard Statements

H226,H301,H310 + H330

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

111.2 °F - closed cup

Flash Point(C)

44 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    SDBB2581
    STBL2345
    STBL0954
    STBK6010
    STBK2077

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    B Setlow et al.
    Applied and environmental microbiology, 64(10), 4109-4112 (1998-10-06)
    The heat resistance of wild-type spores of Bacillus subtilis or spores (termed alpha-beta-) lacking DNA protective alpha/beta-type small, acid-soluble spore proteins was not altered by anaerobiosis or high concentrations of the free radical scavenging agents ethanethiol and ethanedithiol. Heat-killed wild-type
    Joseph M Luther et al.
    ACS nano, 2(2), 271-280 (2009-02-12)
    We describe the structural, optical, and electrical properties of high-quality films of PbSe nanocrystals fabricated by a layer-by-layer (LbL) dip-coating method that utilizes 1,2-ethanedithiol (EDT) as an insolubilizing agent. Comparative characterization of nanocrystal films made by spin-coating and by the
    Misagh Alipour et al.
    The Journal of antimicrobial chemotherapy, 65(4), 684-693 (2010-02-18)
    This study examined the activities of tobramycin and bismuth against quorum sensing, virulence factors and biofilms of Pseudomonas aeruginosa by co-encapsulating the agents in liposomes in order to achieve greater delivery of the agents. The inhibitory effects of the agents
    Majed Halwani et al.
    International journal of pharmaceutics, 358(1-2), 278-284 (2008-05-02)
    Pseudomonas aeruginosa and Burkholderia cenocepacia (formally, genomovar III genotype of Burkholderia cepacia complex) have emerged as serious opportunistic resistant pathogens in patients with cystic fibrosis (CF). We have developed a liposomal formulation containing bismuth-ethanedithiol (BiEDT) and tobramycin to overcome bacterial
    Benjamin J Miller et al.
    The journal of physical chemistry. A, 114(48), 12692-12700 (2010-11-12)
    Vibrational spectra of vapor-phase 1,2-ethanedithiol and 2-mercaptoethanol were recorded to investigate weak intramolecular interactions. The spectra were recorded with conventional absorption spectroscopy and laser photoacoustic spectroscopy in the 2000-11,000 cm(-1) region. The room temperature spectra of each molecule are complicated
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