02270
3′,4′-Dihydroxy-2-(methylamino)acetophenone hydrochloride
≥98.0% (calc. based on dry substance, AT)
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Synonym(s):
Adrenalone hydrochloride
Empirical Formula (Hill Notation):
C9H11NO3 · HCl
CAS Number:
Molecular Weight:
217.65
Beilstein:
3916102
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
≥98.0% (calc. based on dry substance, AT)
impurities
≤10% water
mp
244-249 °C (dec.)
storage temp.
2-8°C
SMILES string
Cl.CNCC(=O)c1ccc(O)c(O)c1
InChI
1S/C9H11NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,10-12H,5H2,1H3;1H
InChI key
CSRRBDMYOUQTCO-UHFFFAOYSA-N
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Related Categories
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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N Bodor et al.
Experimental eye research, 38(6), 621-626 (1984-06-01)
Many diesters of adrenalone have high ocular sympathomimetic activity although adrenalone itself, even if delivered intraocularly, is practically inactive. Thus these diesters cannot be considered pro-drugs of adrenalone, since adrenalone is not a drug. The mechanism of action of these
B Kalyanaraman et al.
The Journal of biological chemistry, 259(1), 354-358 (1984-01-10)
The ESR-spin stabilization approach has been employed to detect and characterize o-semiquinone radicals from the oxidation of epinephrine and related materials (norepinephrine, 3,4-dihydroxynorephedrine, isoproterenol, and adrenalone) in aqueous solutions. Semiquinones were generated by various oxidative procedures--enzymatic oxidation (with horseradish peroxidase/H2O2)
V I Kulinskiĭ et al.
Radiatsionnaia biologiia, radioecologiia, 37(6), 914-917 (1998-02-19)
Experiments are carried out on 3400 mice, irradiated in dose 8 Gy (LD97/30). beta-Ketoanalogs of adrenaline (adrenalone, 50-150 mumol/kg), m,p-dipivaloyladrenaline (20 mumol/kg) and phenylephrine (but at 2070 mumol/kg) have the high radioprotective effect (survival is 60-100%), beta-ketoanalogs of isoprenaline and
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