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Key Documents

Safety Information

01680

Sigma-Aldrich

Acrolein

≥95.0% (as anhydrous, GC)

Synonym(s):

2-Propenal

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About This Item

Linear Formula:
CH2=CHCHO
CAS Number:
Molecular Weight:
56.06
Beilstein:
741856
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

vapor density

1.94 (vs air)

vapor pressure

4.05 psi ( 20 °C)

Assay

≥95.0% (as anhydrous, GC)

autoignition temp.

428 °F

contains

~0.2% hydroquinone as stabilizer
~3% water as stabilizer

expl. lim.

31 %

refractive index

n20/D 1.403 (lit.)
n20/D 1.403

bp

53 °C (lit.)

mp

−87 °C (lit.)

density

0.839 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)C=C

InChI

1S/C3H4O/c1-2-3-4/h2-3H,1H2

InChI key

HGINCPLSRVDWNT-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

-20.2 °F - closed cup

Flash Point(C)

-29 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Kenta Watanabe et al.
Atherosclerosis, 227(1), 51-57 (2013-01-12)
Acrolein-conjugated lysine residues in proteins are present in human atherosclerotic lesions, and are detected in human low-density lipoprotein (LDL). These findings suggest that acrolein may contribute to macrophage foam cell formation and atherogenesis through modification of LDL. The purpose of
Zun-Yi Wang et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 304(10), R846-R853 (2013-03-22)
Cannabinoids have been shown to exert analgesic and anti-inflammatory effects, and the effects of cannabinoids are mediated primarily by cannabinoid receptors 1 and 2 (CB1and CB2). Both CB1 and CB2 are present in bladders of various species, including human, monkey
Rajesh Kasiviswanathan et al.
The Journal of biological chemistry, 288(20), 14247-14255 (2013-04-02)
Acrolein, a mutagenic aldehyde, is produced endogenously by lipid peroxidation and exogenously by combustion of organic materials, including tobacco products. Acrolein reacts with DNA bases forming exocyclic DNA adducts, such as γ-hydroxy-1,N(2)-propano-2'-deoxyguanosine (γ-HOPdG) and γ-hydroxy-1,N(6)-propano-2'-deoxyadenosine (γ-HOPdA). The bulky γ-HOPdG adduct
Stephen C Gammie et al.
PloS one, 3(4), e1974-e1974 (2008-04-10)
Child neglect is the most common form of child maltreatment, yet the biological basis of maternal neglect is poorly understood and a rodent model is lacking. The current study characterizes a population of mice (MaD1) which naturally exhibit maternal neglect
Jianfeng Ma et al.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 19(1), 243-253 (2013-02-06)
Transmission electron microscopy (TEM), fluorescence microscopy, and confocal Raman microscopy can be used to characterize ultrastructural and compositional heterogeneity of plant cell walls. In this study, TEM observations revealed the ultrastructural characterization of Cornus alba L. fiber, vessel, axial parenchyma

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