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Key Documents

Safety Information

00900585

Berberine chloride

primary reference standard

Synonym(s):

Berberine chloride form, Natural Yellow 18

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About This Item

Empirical Formula (Hill Notation):
C20H18ClNO4
CAS Number:
Molecular Weight:
371.81
Colour Index Number:
75160
Beilstein:
3836585
MDL number:
UNSPSC Code:
12352210
NACRES:
NA.24

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grade

primary reference standard

Quality Level

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

SMILES string

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

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1 of 4

This Item
HTS112MHTS170MHTS099M
recombinant

expressed in Chem-9 cells

recombinant

expressed in Chem-1 cells

recombinant

expressed in Chem-1 cells

recombinant

expressed in Chem-1 cells

manufacturer/tradename

ChemiScreen

manufacturer/tradename

ChemiScreen, Chemicon®

manufacturer/tradename

ChemiScreen, Chemicon®

manufacturer/tradename

ChemiScreen, Chemicon®

technique(s)

ligand binding assay: suitable (GTPγS)

technique(s)

ligand binding assay: suitable (GTPγS), radioligand binding assay (RLBA): suitable

technique(s)

ligand binding assay: suitable (GTPγS), radioligand binding assay (RLBA): suitable

technique(s)

ligand binding assay: suitable (GTPγS), radioligand binding assay (RLBA): suitable

NCBI accession no.

NM_002062.2

NCBI accession no.

NM_000160.2

NCBI accession no.

NM_000868

NCBI accession no.

NM_000955

UniProt accession no.

P43220

UniProt accession no.

P47871

UniProt accession no.

P30872

UniProt accession no.

P34995

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Fluorescent stain for heparin in mast cells

Biochem/physiol Actions

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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