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Dextran

analytical standard, for GPC, 270,000

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About This Item

Linear Formula:
[C6H10O5]n
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.24

grade

analytical standard
for GPC

Quality Level

form

powder or crystals

mol wt

Mn ~164200
Mp ~196,300
Mw ~273,000

analyte chemical class(es)

oligosaccharides

technique(s)

gel permeation chromatography (GPC): suitable

Mw/Mn

~1.66

application(s)

food and beverages

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

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General description

Dextran (mol. wt. 270,000) belongs to the family of neutral polysaccharides, which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths. They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.

Application

The analytical standards can also be used as follows:
  • High-performance size exclusion chromatography (HPSEC) based determination of the molecular weight of a dextran synthesized by Leuconostoc citreum B-2, isolated from a fermentation product of pineapple
  • Determination of molecular weight of polysaccharides obtained from four Auricularia species by high-performance liquid chromatography using a water-soluble gel column
  • Identification of molecular weight of a water-soluble polysaccharide isolated by anion exchange chromatography from the dried leaves of C. paliurus by gel permeation chromatography (GPC)
  • Gel permeation chromatography (GPC) based molecular weight measurement of a dextran produced by two strains of Leuconostoc mesenteroides
  • Estimation of molecular weight of a water-soluble polysaccharide obtained from thinned-young apple by high-performance size exclusion chromatography (HPSEC)

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Functional polymers based on dextran
Polysaccharide-based Fibers and Composites: Chemical and Engineering Fundamentals and Industrial Applications, 199-291 (2006)
Dextran?the polysaccharide with versatile uses
Bhavani LA and Nisha J
International Journal of Pharmacy and Biological Sciences, 1(4), 569-573 (2010)
Dmitri Simberg et al.
Biomaterials, 30(23-24), 3926-3933 (2009-04-28)
In order to understand the role of plasma proteins in the rapid liver clearance of dextran-coated superparamagnetic iron oxide (SPIO) in vivo, we analyzed the full repertoire of SPIO-binding blood proteins using novel two-dimensional differential mass spectrometry approach. The identified
Ana Luisa Miranda-Vilela et al.
Journal of biomedical nanotechnology, 9(7), 1261-1271 (2013-08-06)
This work aimed to test a dextran-functionalized magnetic fluid (DexMF) sample in mediating magnetohyperthermia to treat an advanced clinical Ehrlich-solid-tumor, to verify the effects of oral antioxidant administration of pequi-oil on this treatment and to investigate the potential of these
David Needham et al.
Faraday discussions, 161, 515-534 (2013-06-29)
This paper describes how we have used material science, physical chemistry, and some luck, to design a new thermal-sensitive liposome (the low temperature sensitive liposome (LTSL)) that responds at clinically attainable hyperthermic temperatures releasing its drug in a matter of

Related Content

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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