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Dextran

analytical standard, for GPC, 150,000

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About This Item

Linear Formula:
[C6H10O5]n
CAS Number:
9004-54-0
EC Number:
232-677-5
MDL number:
MFCD00130935
UNSPSC Code:
12352201
NACRES:
NA.24

grade

analytical standard
for GPC

Quality Level

100

form

crystalline

mol wt

Mn ~100,300
Mp ~123,600
Mw ~147,600

analyte chemical class(es)

oligosaccharides

technique(s)

gel permeation chromatography (GPC): suitable

Mw/Mn

~1.47

application(s)

food and beverages

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

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General description

Dextran (mol. wt. 150,000) belongs to the family of neutral polysaccharides, which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths. They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.

Application


  • Wound healing hydrogels: Collagen-polyurethane-dextran hydrogels were found to enhance wound healing by reducing inflammation and promoting collagen fibrillogenesis, highlighting dextran′s utility in creating advanced biomaterials for medical applications (Aguayo-Morales et al., 2024).

  • Drug delivery systems: A study on novel dextran bioconjugates for targeted therapy examined their role in enhancing the cellular uptake of antisense oligonucleotides, demonstrating dextran′s critical function in developing more efficient drug delivery systems (Kohashi et al., 2024).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Functional polymers based on dextran
Polysaccharide-based Fibers and Composites: Chemical and Engineering Fundamentals and Industrial Applications, 199-291 (2006)
Dextran?the polysaccharide with versatile uses
Bhavani LA and Nisha J
International Journal of Pharmacy and Biological Sciences, 1(4), 569-573 (2010)
Dmitri Simberg et al.
Biomaterials, 30(23-24), 3926-3933 (2009-04-28)
In order to understand the role of plasma proteins in the rapid liver clearance of dextran-coated superparamagnetic iron oxide (SPIO) in vivo, we analyzed the full repertoire of SPIO-binding blood proteins using novel two-dimensional differential mass spectrometry approach. The identified
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
David Needham et al.
Faraday discussions, 161, 515-534 (2013-06-29)
This paper describes how we have used material science, physical chemistry, and some luck, to design a new thermal-sensitive liposome (the low temperature sensitive liposome (LTSL)) that responds at clinically attainable hyperthermic temperatures releasing its drug in a matter of
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Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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