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Product Name
Ginsenoside Rb1, primary reference standard
InChI
1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/m0/s1
InChI key
GZYPWOGIYAIIPV-JBDTYSNRSA-N
SMILES string
C\C(C)=C\CC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)[C@@H]3[C@H](O)C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)[C@@H]6CC[C@@]45C
grade
primary reference standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
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Application
- Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of ginsenoside Rb1, naringin, ginsenoside Rb2, and oridonin in rat plasma samples after administrating them weifuchun tablets
- Multi-residue analysis of baicalin, baicalein, wogonoside, wogonin, scutellarin, berberine, coptisine, ginsenoside Rb1, and ginsenoside Re in biological samples of rat plasma by liquid chromatographic-tandem mass spectrometric (LC/MS/MS) method
- Analysis of traditional Chinese herbal decoctions of Dushen Tang and Shenfu Tang for the quantification of 12 ginsenosides by UPLC-MS/MS technique
- Analysis of rhizomes and roots of ginseng for the detection of 131 ginsenosides by UHPLC combined with a diode-array detector and quadrupole/time of flight tandem mass spectrometry (DAD-QTOF-MS/MS), along with the further determination of 19 ginsenosides by HPLC coupled with electrospray ionization-mass spectrometric detection
General description
Exact content measured by quantitative NMR can be found on the certificate.
Ginsenoside Rb1 is one of the primary constituents of traditional Chinese medicine, Ginseng. It belongs to the group of triterpene saponins called ginsenosides and pharmacologically, it is one of the most active dammarane-type ginsenosides. It is known to have anti-tumor, anti-oxidant, anti-inflammatory, and cytoprotective properties.
Other Notes
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.
Method development for HPLC-UV quantification of tanshinone IIA and key ginsenosides in Guanxin Danshen Diwan as per the Chinese Pharmacopoeia draft.
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